Antibody reactivity against EBNA1 and GlialCAM differentiates multiple sclerosis patients from healthy controls

Multiple sclerosis (MS) is an autoimmune demyelinating disorder of the central nervous system (CNS), which is linked to Epstein-Barr virus (EBV) infection, preceding the disease. The molecular mechanisms underlying this connection are only partially understood. We previously described molecular mimi...

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Vydáno v:	Proceedings of the National Academy of Sciences - PNAS Ročník 122; číslo 11; s. e2424986122
Hlavní autoři:	Sattarnezhad, Neda, Kockum, Ingrid, Thomas, Olivia G, Liu, Yicong, Ho, Peggy P, Barrett, Alison K, Comanescu, Alexandros I, Wijeratne, Tilini U, Utz, Paul J, Alfredsson, Lars, Steinman, Lawrence, Robinson, William H, Olsson, Tomas, Lanz, Tobias V
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	United States 18.03.2025
Témata:	Adult Case-Control Studies Cross Reactions Epstein-Barr Virus Nuclear Antigens - immunology Female Herpesvirus 4, Human - immunology HLA-DRB1 Chains - genetics HLA-DRB1 Chains - immunology Humans Immunoglobulin G - immunology Male Middle Aged Molecular Mimicry - immunology Multiple Sclerosis - diagnosis Multiple Sclerosis - genetics Multiple Sclerosis - immunology Multiple Sclerosis - virology molecular mimicry GlialCAM antibodies multiple sclerosis Epstein–Barr virus
ISSN:	1091-6490, 1091-6490
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