Efficient ancestry and mutation simulation with msprime 1.0

Abstract Stochastic simulation is a key tool in population genetics, since the models involved are often analytically intractable and simulation is usually the only way of obtaining ground-truth data to evaluate inferences. Because of this, a large number of specialized simulation programs have been...

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Vydáno v:	Genetics (Austin) Ročník 220; číslo 3
Hlavní autoři:	Baumdicker, Franz, Bisschop, Gertjan, Goldstein, Daniel, Gower, Graham, Ragsdale, Aaron P, Tsambos, Georgia, Zhu, Sha, Eldon, Bjarki, Ellerman, E Castedo, Galloway, Jared G, Gladstein, Ariella L, Gorjanc, Gregor, Guo, Bing, Jeffery, Ben, Kretzschumar, Warren W, Lohse, Konrad, Matschiner, Michael, Nelson, Dominic, Pope, Nathaniel S, Quinto-Cortés, Consuelo D, Rodrigues, Murillo F, Saunack, Kumar, Sellinger, Thibaut, Thornton, Kevin, van Kemenade, Hugo, Wohns, Anthony W, Wong, Yan, Gravel, Simon, Kern, Andrew D, Koskela, Jere, Ralph, Peter L, Kelleher, Jerome
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	United States Oxford University Press 03.03.2022
Témata:	Algorithms Computer Simulation Genetics, Population Models, Genetic Mutation Software mutations Ancestral Recombination Graphs simulation coalescent
ISSN:	1943-2631, 1943-2631
On-line přístup:	Získat plný text
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