Generation of a double binary transgenic zebrafish model to study myeloid gene regulation in response to oncogene activation in melanocytes

A complex network of inflammation succeeds somatic cell transformation and malignant disease. Immune cells and their associated molecules are responsible for detecting and eliminating cancer cells as they establish themselves as the precursors of a tumour. By the time a patient has a detectable soli...

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Vydané v:	Disease models & mechanisms Ročník 11; číslo 4
Hlavní autori:	Kenyon, Amy, Gavriouchkina, Daria, Zorman, Jernej, Chong-Morrison, Vanessa, Napolitani, Giorgio, Cerundolo, Vincenzo, Sauka-Spengler, Tatjana
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	England The Company of Biologists Ltd 01.04.2018 The Company of Biologists
Predmet:	Animals Animals, Genetically Modified Artificial chromosomes Binding sites Biotagging Cancer Cell Line, Transformed Cell Proliferation Cell Shape DNA methylation Embryos Gene expression Gene Expression Profiling Gene Expression Regulation Genes, ras Genetic engineering Genomes Ligands Macrophage Melanocyte Melanocytes - metabolism Melanocytes - pathology Melanoma Melanoma - genetics Melanoma - pathology Mifepristone Models, Animal Mutation Myeloid Cells - metabolism Neutrophil Neutrophils Neutrophils - metabolism Oncogene Oncogenes Proteins Resource Transcription factors Transcription, Genetic Zebrafish Zebrafish - genetics Zebrafish Biotagging Neutrophil Oncogene Melanocyte Macrophage
ISSN:	1754-8403, 1754-8411, 1754-8411
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