A systematic comparison of pharmacogene star allele calling bioinformatics algorithms: a focus on CYP2D6 genotyping

Genetic variation in genes encoding cytochrome P450 enzymes has important clinical implications for drug metabolism. Bioinformatics algorithms for genotyping these highly polymorphic genes using high-throughput sequence data and automating phenotype prediction have recently been developed. The CYP2D...

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Bibliographic Details

Published in:	Npj genomic medicine Vol. 5; no. 1; p. 30
Main Authors:	Twesigomwe, David, Wright, Galen E. B., Drögemöller, Britt I., da Rocha, Jorge, Lombard, Zané, Hazelhurst, Scott
Format:	Journal Article
Language:	English
Published:	London Nature Publishing Group UK 03.08.2020 Nature Publishing Group
Subjects:	631/114/2785 631/208/212/1728 631/208/727/728 Algorithms Bioinformatics Biomedical and Life Sciences Biomedicine Gene Function Gene Therapy Haplotypes Human Genetics Internal Medicine Haplotypes Genome informatics Pharmacogenomics
ISSN:	2056-7944, 2056-7944
Online Access:	Get full text
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