Sodium arsenite induces apoptosis and Epstein–Barr virus reactivation in lymphoblastoid cells

Epstein–Barr virus (EBV) is associated with several malignancies, including carcinomas, such as nasopharyngeal carcinoma, and lymphomas, such as Burkitt's lymphoma and Hodgkin's lymphoma. The Latent Membrane Protein 1 (LMP1) is the major oncogene protein of EBV as its expression is respons...

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Bibliographic Details
Published in:	Biochimie Vol. 107; pp. 247 - 256
Main Authors:	Zebboudj, Abderezak, Maroui, Mohamed Ali, Dutrieux, Jacques, Touil-Boukoffa, Chafia, Bourouba, Mehdi, Chelbi-Alix, Mounira K., Nisole, Sébastien
Format:	Journal Article
Language:	English
Published:	France Elsevier B.V 01.12.2014
Subjects:	Antigens, Nuclear - metabolism apoptosis Apoptosis - drug effects Arsenic Arsenic Trioxide Arsenicals - pharmacology Arsenites - pharmacology Autoantigens - metabolism autophagy Autophagy - drug effects Burkitt Lymphoma - pathology Burkitt Lymphoma - virology carcinoma cell growth Cell Line, Tumor - drug effects Cell Proliferation - drug effects cytotoxicity Epstein-Barr virus flow cytometry Herpesvirus 4, Human - drug effects Herpesvirus 4, Human - metabolism Hodgkin disease Human gammaherpesvirus 4 Humans Latency LMP1 membrane proteins neoplasm cells Nuclear Proteins - metabolism oncogene proteins Oxides - pharmacology PML Promyelocytic Leukemia Protein sodium arsenite Sodium Compounds - pharmacology Transcription Factors - metabolism Tumor Suppressor Proteins - metabolism Viral Matrix Proteins - metabolism Western blotting LMP1 Arsenic Epstein–Barr virus PML Latency
ISSN:	0300-9084, 1638-6183, 1638-6183
Online Access:	Get full text
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