Peripheral and central pathogenesis of postherpetic neuralgia
Background Postherpetic neuralgia (PHN) is a classic chronic condition with multiple signs of peripheral and central neuropathy. Unfortunately, the pathogenesis of PHN is not well defined, limiting clinical treatment and disease management. Objective To describe the peripheral and central pathologic...
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| Published in: | Skin research and technology Vol. 30; no. 8; pp. e13867 - n/a |
|---|---|
| Main Authors: | , , |
| Format: | Journal Article |
| Language: | English |
| Published: |
England
John Wiley & Sons, Inc
01.08.2024
John Wiley and Sons Inc |
| Subjects: | |
| ISSN: | 0909-752X, 1600-0846, 1600-0846 |
| Online Access: | Get full text |
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| Abstract | Background
Postherpetic neuralgia (PHN) is a classic chronic condition with multiple signs of peripheral and central neuropathy. Unfortunately, the pathogenesis of PHN is not well defined, limiting clinical treatment and disease management.
Objective
To describe the peripheral and central pathological axes of PHN, including peripheral nerve injury, inflammation induction, central nervous system sensitization, and brain functional and structural network activity.
Methods
A bibliographic survey was carried out, selecting relevant articles that evaluated the characterization of the pathogenesis of PHN, including peripheral and central pathological axes.
Results
Currently, due to the complexity of the pathophysiological mechanisms of PHN and the incomplete understanding of the exact mechanism of neuralgia.
Conclusion
It is essential to conduct in‐depth research to clarify the origins of PHN pathogenesis and explore effective and comprehensive therapies for PHN. |
|---|---|
| AbstractList | Background
Postherpetic neuralgia (PHN) is a classic chronic condition with multiple signs of peripheral and central neuropathy. Unfortunately, the pathogenesis of PHN is not well defined, limiting clinical treatment and disease management.
Objective
To describe the peripheral and central pathological axes of PHN, including peripheral nerve injury, inflammation induction, central nervous system sensitization, and brain functional and structural network activity.
Methods
A bibliographic survey was carried out, selecting relevant articles that evaluated the characterization of the pathogenesis of PHN, including peripheral and central pathological axes.
Results
Currently, due to the complexity of the pathophysiological mechanisms of PHN and the incomplete understanding of the exact mechanism of neuralgia.
Conclusion
It is essential to conduct in‐depth research to clarify the origins of PHN pathogenesis and explore effective and comprehensive therapies for PHN. Background Postherpetic neuralgia (PHN) is a classic chronic condition with multiple signs of peripheral and central neuropathy. Unfortunately, the pathogenesis of PHN is not well defined, limiting clinical treatment and disease management. Objective To describe the peripheral and central pathological axes of PHN, including peripheral nerve injury, inflammation induction, central nervous system sensitization, and brain functional and structural network activity. Methods A bibliographic survey was carried out, selecting relevant articles that evaluated the characterization of the pathogenesis of PHN, including peripheral and central pathological axes. Results Currently, due to the complexity of the pathophysiological mechanisms of PHN and the incomplete understanding of the exact mechanism of neuralgia. Conclusion It is essential to conduct in‐depth research to clarify the origins of PHN pathogenesis and explore effective and comprehensive therapies for PHN. Postherpetic neuralgia (PHN) is a classic chronic condition with multiple signs of peripheral and central neuropathy. Unfortunately, the pathogenesis of PHN is not well defined, limiting clinical treatment and disease management.BACKGROUNDPostherpetic neuralgia (PHN) is a classic chronic condition with multiple signs of peripheral and central neuropathy. Unfortunately, the pathogenesis of PHN is not well defined, limiting clinical treatment and disease management.To describe the peripheral and central pathological axes of PHN, including peripheral nerve injury, inflammation induction, central nervous system sensitization, and brain functional and structural network activity.OBJECTIVETo describe the peripheral and central pathological axes of PHN, including peripheral nerve injury, inflammation induction, central nervous system sensitization, and brain functional and structural network activity.A bibliographic survey was carried out, selecting relevant articles that evaluated the characterization of the pathogenesis of PHN, including peripheral and central pathological axes.METHODSA bibliographic survey was carried out, selecting relevant articles that evaluated the characterization of the pathogenesis of PHN, including peripheral and central pathological axes.Currently, due to the complexity of the pathophysiological mechanisms of PHN and the incomplete understanding of the exact mechanism of neuralgia.RESULTSCurrently, due to the complexity of the pathophysiological mechanisms of PHN and the incomplete understanding of the exact mechanism of neuralgia.It is essential to conduct in-depth research to clarify the origins of PHN pathogenesis and explore effective and comprehensive therapies for PHN.CONCLUSIONIt is essential to conduct in-depth research to clarify the origins of PHN pathogenesis and explore effective and comprehensive therapies for PHN. Postherpetic neuralgia (PHN) is a classic chronic condition with multiple signs of peripheral and central neuropathy. Unfortunately, the pathogenesis of PHN is not well defined, limiting clinical treatment and disease management. To describe the peripheral and central pathological axes of PHN, including peripheral nerve injury, inflammation induction, central nervous system sensitization, and brain functional and structural network activity. A bibliographic survey was carried out, selecting relevant articles that evaluated the characterization of the pathogenesis of PHN, including peripheral and central pathological axes. Currently, due to the complexity of the pathophysiological mechanisms of PHN and the incomplete understanding of the exact mechanism of neuralgia. It is essential to conduct in-depth research to clarify the origins of PHN pathogenesis and explore effective and comprehensive therapies for PHN. |
| Author | Liu, Qiuping Han, Jingxian Zhang, Xuezhu |
| AuthorAffiliation | 3 Department of Rheumatology and Immunology First Affiliated Hospital of Army Medical University Chongqing China 1 First Teaching Hospital of Tianjin University of Traditional Chinese Medicine Tianjin China 2 National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion Tianjin China |
| AuthorAffiliation_xml | – name: 3 Department of Rheumatology and Immunology First Affiliated Hospital of Army Medical University Chongqing China – name: 2 National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion Tianjin China – name: 1 First Teaching Hospital of Tianjin University of Traditional Chinese Medicine Tianjin China |
| Author_xml | – sequence: 1 givenname: Qiuping surname: Liu fullname: Liu, Qiuping organization: First Affiliated Hospital of Army Medical University – sequence: 2 givenname: Jingxian surname: Han fullname: Han, Jingxian organization: National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion – sequence: 3 givenname: Xuezhu surname: Zhang fullname: Zhang, Xuezhu email: zhangxuezhu1999@126.com organization: National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/39101621$$D View this record in MEDLINE/PubMed |
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Postherpetic neuralgia (PHN) is a classic chronic condition with multiple signs of peripheral and central neuropathy. Unfortunately, the... Postherpetic neuralgia (PHN) is a classic chronic condition with multiple signs of peripheral and central neuropathy. Unfortunately, the pathogenesis of PHN is... Background Postherpetic neuralgia (PHN) is a classic chronic condition with multiple signs of peripheral and central neuropathy. Unfortunately, the... |
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| SubjectTerms | Brain - pathology Brain - physiopathology Brain injury central Central nervous system Central Nervous System Sensitization - physiology Humans Injury prevention mechanism Neuralgia Neuralgia, Postherpetic - physiopathology Neuropathy Original Pathogenesis peripheral Peripheral Nerve Injuries - physiopathology Peripheral nerves Peripheral neuropathy postherpetic neuralgia Structural analysis Structure-function relationships |
| Title | Peripheral and central pathogenesis of postherpetic neuralgia |
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