Comprehensive analysis of the cytokine-rich chromosome 5q31.1 region suggests a role for IL-4 gene variants in prostate cancer risk

Although inflammation is emerging as a candidate prostate cancer risk factor, the T-helper cytokine-rich [interleukins (IL)-5, 13 and 4] chromosomal region at 5q31.1 has been implicated in prostate cancer pathogenesis. In particular, IL-4 has been associated with prostate cancer progression, whereas...

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Vydané v:	Carcinogenesis (New York) Ročník 31; číslo 10; s. 1748
Hlavní autori:	Tindall, E A, Severi, G, Hoang, H N, Ma, C S, Fernandez, P, Southey, M C, English, D R, Hopper, J L, Heyns, C F, Tangye, S G, Giles, G G, Hayes, V M
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	England 01.10.2010
Predmet:	Chromosomes, Human, Pair 5 Genetic Predisposition to Disease Genotype Haplotypes Humans Interleukin-4 - blood Interleukin-4 - genetics Male Polymorphism, Single Nucleotide Promoter Regions, Genetic Prostatic Neoplasms - genetics RNA, Messenger - analysis
ISSN:	1460-2180, 1460-2180
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