Effects of Recombinant Human Leptin (Metreleptin) on Nocturnal Luteinizing Hormone Secretion in Lipodystrophy Patients

Leptin replacement in patients with leptin gene mutations improves hypogonadotropic hypogonadism. The effects of leptin replacement on luteinizing hormone (LH) secretion in patients with lipodystrophy are unknown. We examined nocturnal LH secretory dynamics on and off exogenous leptin therapy using...

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Bibliographic Details

Published in:	Neuroendocrinology Vol. 103; no. 3-4; p. 402
Main Authors:	Abel, Brent S, Muniyappa, Ranganath, Stratton, Pamela, Skarulis, Monica C, Gorden, Phillip, Brown, Rebecca J
Format:	Journal Article
Language:	English
Published:	Switzerland 01.01.2016
Subjects:	Adult Circadian Rhythm - physiology Enzyme-Linked Immunosorbent Assay Female Humans Leptin - analogs & derivatives Leptin - therapeutic use Lipodystrophy - drug therapy Luteinizing Hormone - metabolism Male Middle Aged Steroids - metabolism Young Adult
ISSN:	1423-0194, 1423-0194
Online Access:	Get more information
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