Inflammation-induced uptake and degradation of the lymphatic endothelial hyaluronan receptor LYVE-1

The hyaluronan receptor LYVE-1 is selectively expressed in the endothelium of lymphatic capillaries, where it has been proposed to function in hyaluronan clearance and hyaluronan-mediated leukocyte adhesion. However, recent studies suggest that hyaluronan homeostasis is unperturbed in LYVE-1(-/-) mi...

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Veröffentlicht in:	The Journal of biological chemistry Jg. 282; H. 46; S. 33671
Hauptverfasser:	Johnson, Louise A, Prevo, Remko, Clasper, Steven, Jackson, David G
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States 16.11.2007
Schlagworte:	Allergens - chemistry Animals Cell Adhesion Gene Expression Regulation Glycoproteins - metabolism Humans Hyaluronic Acid - metabolism Inflammation Leukocytes - metabolism Lymphangiogenesis Lymphatic System - metabolism Lysosomes - metabolism Male Membrane Transport Proteins Mice Mice, Inbred BALB C Mice, Inbred C57BL Vascular Cell Adhesion Molecule-1 - metabolism Vesicular Transport Proteins - metabolism
ISSN:	0021-9258
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