Low-dose radiotherapy promotes the formation of tertiary lymphoid structures in lung adenocarcinoma

A tertiary lymphoid structure (TLS) refers to an organized infiltration of immune cells that is linked to a positive prognosis and improved response to immunotherapy. However, methods that promote TLS formation are limited and challenging to implement in clinical settings. In this study, we aimed to...

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Bibliographic Details
Published in:	Frontiers in immunology Vol. 14; p. 1334408
Main Authors:	Wang, Duo, Huang, Liuying, Qian, Danqi, Cao, Yulin, Wu, Xiaohan, Xu, Peiwen, Ming, Liang, Tang, Junhui, Huang, Zhaohui, Yin, Yuan, Zhou, Leyuan
Format:	Journal Article
Language:	English
Published:	Switzerland Frontiers Media SA 08.01.2024 Frontiers Media S.A
Subjects:	Adenocarcinoma Adenocarcinoma - radiotherapy Adenocarcinoma of Lung - radiotherapy Alcohol Animals Antibodies Antigens Antitumor activity Cancer therapies CD8 antigen Dendritic cells Disease Models, Animal Humans Immunology Immunotherapy low dose radiotherapy Lung cancer Lung Neoplasms - radiotherapy Lymphocytes T Maturation Medical prognosis Medical research Mice Optimization techniques Patients PD-1 protein Prognosis Proto-Oncogene Proteins p21(ras) - genetics Radiation therapy Risk factors Tertiary Lymphoid Structures tumor microenvironment Tumors lung cancer low dose radiotherapy tumor microenvironment immunotherapy tertiary lymphoid structures
ISSN:	1664-3224, 1664-3224
Online Access:	Get full text
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