Repositioning TH cell polarization from single cytokines to complex help

When helper T (T H ) cell polarization was initially described three decades ago, the T H cell universe grew dramatically. New subsets were described based on their expression of few specific cytokines. Beyond T H 1 and T H 2 cells, this led to the coining of various T H 17 and regulatory (T reg ) c...

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Bibliographic Details
Published in:	Nature immunology Vol. 22; no. 10; pp. 1210 - 1217
Main Authors:	Tuzlak, Selma, Dejean, Anne S., Iannacone, Matteo, Quintana, Francisco J., Waisman, Ari, Ginhoux, Florent, Korn, Thomas, Becher, Burkhard
Format:	Journal Article
Language:	English
Published:	New York Nature Publishing Group US 01.10.2021 Nature Publishing Group
Subjects:	631/250/1619/554/1898 692/420/256 Animals B-Lymphocytes / immunology Biomedical and Life Sciences Biomedicine Cell Plasticity / immunology Cellular Biology Cytokines Cytokines / immunology Eosinophils / immunology Epithelium Epithelium / immunology Helper cells Humans Immunity, Innate / immunology Immunology Infectious Diseases Leukocytes (eosinophilic) Life Sciences Lymphocytes / immunology Lymphocytes B Lymphocytes T Lymphoid cells Mast cells Perspective Phagocytes Phagocytes / immunology Polarization Stroma T-Lymphocytes, Helper-Inducer / immunology Transcription factors
ISSN:	1529-2908, 1529-2916, 1529-2916
Online Access:	Get full text
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