Evidence for Shaping of Light Chain Repertoire by Structural Selection

The naïve immunoglobulin (IG) repertoire in the blood differs from the direct output of the rearrangement process. These differences stem from selection that affects the germline gene usage and the junctional nucleotides. A major complication obscuring the details of the selection mechanism in the h...

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Vydané v:	Frontiers in immunology Ročník 9; s. 1307
Hlavní autori:	Toledano, Adar, Elhanati, Yuval, Benichou, Jennifer I. C., Walczak, Aleksandra M., Mora, Thierry, Louzoun, Yoram
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	Switzerland Frontiers 22.06.2018 Frontiers Media S.A
Predmet:	B cell receptor deep sequencing Immunology Life Sciences light chain Mathematics Physics rearrangement selection light chain selection B cell receptor deep sequencing rearrangement
ISSN:	1664-3224, 1664-3224
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