Evidence for Shaping of Light Chain Repertoire by Structural Selection

The naïve immunoglobulin (IG) repertoire in the blood differs from the direct output of the rearrangement process. These differences stem from selection that affects the germline gene usage and the junctional nucleotides. A major complication obscuring the details of the selection mechanism in the h...

Full description

Bibliographic Details

Published in:	Frontiers in immunology Vol. 9; p. 1307
Main Authors:	Toledano, Adar, Elhanati, Yuval, Benichou, Jennifer I. C., Walczak, Aleksandra M., Mora, Thierry, Louzoun, Yoram
Format:	Journal Article
Language:	English
Published:	Switzerland Frontiers 22.06.2018 Frontiers Media S.A
Subjects:	B cell receptor deep sequencing Immunology Life Sciences light chain Mathematics Physics rearrangement selection light chain selection B cell receptor deep sequencing rearrangement
ISSN:	1664-3224, 1664-3224
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!