Cytokine profile in plasma of severe COVID-19 does not differ from ARDS and sepsis

BACKGROUNDElevated levels of inflammatory cytokines have been associated with poor outcomes among COVID-19 patients. It is unknown, however, how these levels compare with those observed in critically ill patients with acute respiratory distress syndrome (ARDS) or sepsis due to other causes.METHODSWe...

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Bibliographic Details
Published in:	JCI insight Vol. 5; no. 17
Main Authors:	Wilson, Jennifer G., Simpson, Laura J., Ferreira, Anne-Maud, Rustagi, Arjun, Roque, Jonasel, Asuni, Adijat, Ranganath, Thanmayi, Grant, Philip M., Subramanian, Aruna, Rosenberg-Hasson, Yael, Maecker, Holden T., Holmes, Susan P., Levitt, Joseph E., Blish, Catherine A., Rogers, Angela J.
Format:	Journal Article
Language:	English
Published:	United States American Society for Clinical Investigation 03.09.2020 American Society for Clinical investigation
Subjects:	Adult Aged Biomarkers Case-Control Studies Clinical Medicine Coronavirus Infections - blood Coronavirus Infections - immunology COVID-19 Cytokine Release Syndrome - blood Cytokine Release Syndrome - immunology Cytokine storm Cytokines - blood Cytokines - immunology Disease Female Hospitalization Humans IL-1β Immunosuppressive agents Infectious diseases Inflammation Interleukin 1 receptor antagonist Interleukin 1 Receptor Antagonist Protein - blood Interleukin 1 Receptor Antagonist Protein - immunology Interleukin 1 receptors Interleukin 18 Interleukin 6 Interleukin 8 Interleukin-18 - blood Interleukin-18 - immunology Interleukin-1beta - blood Interleukin-1beta - immunology Interleukin-6 - blood Interleukin-6 - immunology Interleukin-8 - blood Interleukin-8 - immunology Male Middle Aged Pandemics Patients Plasma Pneumonia, Viral - blood Pneumonia, Viral - immunology Respiratory distress syndrome Respiratory Distress Syndrome - blood Respiratory Distress Syndrome - immunology Sepsis Sepsis - blood Sepsis - immunology Severity of Illness Index Statistical analysis Tumor Necrosis Factor-alpha - blood Tumor Necrosis Factor-alpha - immunology Tumor necrosis factor-α Ventilation Ventilators COVID-19 Cytokines Inflammation
ISSN:	2379-3708, 2379-3708
Online Access:	Get full text
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