The Role of Bacteria in the Pathogenesis and Progression of Idiopathic Pulmonary Fibrosis

Idiopathic pulmonary fibrosis (IPF) is a progressive lung disease of unknown cause that leads to respiratory failure and death within 5 years of diagnosis. Overt respiratory infection and immunosuppression carry a high morbidity and mortality, and polymorphisms in genes related to epithelial integri...

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Bibliographic Details
Published in:	American journal of respiratory and critical care medicine Vol. 190; no. 8; pp. 906 - 913
Main Authors:	Molyneaux, Phillip L., Cox, Michael J., Willis-Owen, Saffron A. G., Mallia, Patrick, Russell, Kirsty E., Russell, Anne-Marie, Murphy, Elissa, Johnston, Sebastian L., Schwartz, David A., Wells, Athol U., Cookson, William O. C., Maher, Toby M., Moffatt, Miriam F.
Format:	Journal Article
Language:	English
Published:	United States American Thoracic Society 15.10.2014
Subjects:	Aged Bacteria Bacteria - isolation & purification Bacterial Load Bronchoalveolar Lavage Bronchoalveolar Lavage Fluid - microbiology Bronchoscopy Case-Control Studies Chronic obstructive pulmonary disease Disease Progression DNA, Bacterial - analysis Female Genes Genetic Markers Genotyping Techniques Humans Idiopathic Pulmonary Fibrosis - genetics Idiopathic Pulmonary Fibrosis - microbiology Idiopathic Pulmonary Fibrosis - mortality Idiopathic Pulmonary Fibrosis - physiopathology Infections Lavage Logistic Models Lung diseases Male Microbiota Middle Aged Mortality Mucin-5B - genetics Original Pathogenesis Polymerase Chain Reaction Polymorphism Polymorphism, Genetic Prospective Studies Pulmonary fibrosis Sequence Analysis, DNA Taxonomy Muc5b idiopathic pulmonary fibrosis bacteria microbiome
ISSN:	1073-449X, 1535-4970, 1535-4970
Online Access:	Get full text
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