Mitochondrial calcium cycling in neuronal function and neurodegeneration

Mitochondria are essential for proper cellular function through their critical roles in ATP synthesis, reactive oxygen species production, calcium (Ca 2+ ) buffering, and apoptotic signaling. In neurons, Ca 2+ buffering is particularly important as it helps to shape Ca 2+ signals and to regulate num...

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Bibliographic Details
Published in:	Frontiers in cell and developmental biology Vol. 11; p. 1094356
Main Authors:	Walters, Grant C., Usachev, Yuriy M.
Format:	Journal Article
Language:	English
Published:	Switzerland Frontiers Media SA 24.01.2023 Frontiers Media S.A
Subjects:	Alzheimer's disease Amyotrophic lateral sclerosis Apoptosis calcium Calcium (mitochondrial) Calcium buffering Calcium influx Calcium signalling Calcium transport Cell and Developmental Biology Dehydrogenases Disease Epilepsy Excitability Gene expression MCU Mitochondria Mutation Neurodegeneration Neurodegenerative diseases Neurological diseases neuronal calcium homeostasis Neurotoxicity Oxidative stress Parkinson's disease Permeability Physiology Reactive oxygen species Synaptic transmission neurodegeneration calcium mitochondria MCU neuronal calcium homeostasis
ISSN:	2296-634X, 2296-634X
Online Access:	Get full text
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