LncRNA VEAL2 regulates PRKCB2 to modulate endothelial permeability in diabetic retinopathy

Long non‐coding RNAs (lncRNAs) are emerging as key regulators of endothelial cell function. Here, we investigated the role of a novel vascular endothelial‐associated lncRNA ( VEAL2 ) in regulating endothelial permeability. Precise editing of veal2 loci in zebrafish ( veal2 gib005Δ8/+ ) induced crani...

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Veröffentlicht in:	The EMBO journal Jg. 40; H. 15; S. e107134 - n/a
Hauptverfasser:	Sehgal, Paras, Mathew, Samatha, Sivadas, Ambily, Ray, Arjun, Tanwar, Jyoti, Vishwakarma, Sushma, Ranjan, Gyan, Shamsudheen, K V, Bhoyar, Rahul C, Pateria, Abhishek, Leonard, Elvin, Lalwani, Mukesh, Vats, Archana, Pappuru, Rajeev R, Tyagi, Mudit, Jakati, Saumya, Sengupta, Shantanu, B K, Binukumar, Chakrabarti, Subhabrata, Kaur, Inderjeet, Motiani, Rajender K, Scaria, Vinod, Sivasubbu, Sridhar
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	London Nature Publishing Group UK 02.08.2021 Springer Nature B.V John Wiley and Sons Inc
Schlagworte:	Baits Competition Danio rerio Diabetes Diabetes mellitus Diabetic retinopathy diacylglycerol Diglycerides Ectopic expression EMBO05 EMBO36 EMBO46 Endothelial cells endothelial permeability Endothelium Hemorrhage In vivo methods and tests Kinases long non‐coding RNA Non-coding RNA Permeability Protein kinase C protein kinase C beta Proteins Retinopathy Zebrafish protein kinase C beta diabetic retinopathy endothelial permeability diacylglycerol long non‐coding RNA
ISSN:	0261-4189, 1460-2075, 1460-2075
Online-Zugang:	Volltext
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