Longitudinal spinal cord atrophy in multiple sclerosis using the generalized boundary shift integral

Objective Spinal cord atrophy is a clinically relevant feature of multiple sclerosis (MS), but longitudinal assessments on magnetic resonance imaging using segmentation‐based methods suffer from measurement variability, especially in multicenter studies. We compared the generalized boundary shift in...

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Bibliographic Details
Published in:	Annals of neurology Vol. 86; no. 5; pp. 704 - 713
Main Authors:	Moccia, Marcello, Prados, Ferran, Filippi, Massimo, Rocca, Maria A., Valsasina, Paola, Brownlee, Wallace J., Zecca, Chiara, Gallo, Antonio, Rovira, Alex, Gass, Achim, Palace, Jacqueline, Lukas, Carsten, Vrenken, Hugo, Ourselin, Sebastien, Gandini Wheeler‐Kingshott, Claudia A. M., Ciccarelli, Olga, Barkhof, Frederik
Format:	Journal Article
Language:	English
Published:	Hoboken, USA John Wiley & Sons, Inc 01.11.2019 Wiley Subscription Services, Inc
Subjects:	Adult Atrophy Atrophy - pathology Female Humans Image Interpretation, Computer-Assisted - methods Image processing Image segmentation Integrals Magnetic resonance imaging Magnetic Resonance Imaging - methods Male Mathematical analysis Measurement methods Middle Aged Multiple sclerosis Multiple Sclerosis - diagnostic imaging Multiple Sclerosis - pathology Neuroimaging - methods NMR Nuclear magnetic resonance Registration Resonance Retrospective Studies Spinal cord Spinal Cord - diagnostic imaging Spinal Cord - pathology Statistical analysis Variability
ISSN:	0364-5134, 1531-8249, 1531-8249
Online Access:	Get full text
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