ACG Clinical Guidelines: Prevention, Diagnosis, and Treatment of Clostridioides difficile Infections
Clostridioides difficile infection occurs when the bacterium produces toxin that causes diarrhea and inflammation of the colon. These guidelines indicate the preferred approach to the management of adults with C. difficile infection and represent the official practice recommendations of the American...
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| Veröffentlicht in: | The American journal of gastroenterology Jg. 116; H. 6; S. 1124 - 1147 |
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| Hauptverfasser: | , , , , , , |
| Format: | Journal Article |
| Sprache: | Englisch |
| Veröffentlicht: |
United States
Wolters Kluwer
01.06.2021
Wolters Kluwer Health Medical Research, Lippincott Williams & Wilkins |
| Schlagworte: | |
| ISSN: | 0002-9270, 1572-0241, 1572-0241 |
| Online-Zugang: | Volltext |
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| Abstract | Clostridioides difficile infection occurs when the bacterium produces toxin that causes diarrhea and inflammation of the colon. These guidelines indicate the preferred approach to the management of adults with C. difficile infection and represent the official practice recommendations of the American College of Gastroenterology. The scientific evidence for these guidelines was evaluated using the Grading of Recommendations Assessment, Development, and Evaluation process. In instances where the evidence was not appropriate for Grading of Recommendations Assessment, Development, and Evaluation but there was consensus of significant clinical merit, key concept statements were developed using expert consensus. These guidelines are meant to be broadly applicable and should be viewed as the preferred, but not the only, approach to clinical scenarios. |
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| AbstractList | Clostridioides difficile infection occurs when the bacterium produces toxin that causes diarrhea and inflammation of the colon. These guidelines indicate the preferred approach to the management of adults with C. difficile infection and represent the official practice recommendations of the American College of Gastroenterology. The scientific evidence for these guidelines was evaluated using the Grading of Recommendations Assessment, Development, and Evaluation process. In instances where the evidence was not appropriate for Grading of Recommendations Assessment, Development, and Evaluation but there was consensus of significant clinical merit, key concept statements were developed using expert consensus. These guidelines are meant to be broadly applicable and should be viewed as the preferred, but not the only, approach to clinical scenarios. Clostridioides difficile infection occurs when the bacterium produces toxin that causes diarrhea and inflammation of the colon. These guidelines indicate the preferred approach to the management of adults with C. difficile infection and represent the official practice recommendations of the American College of Gastroenterology. The scientific evidence for these guidelines was evaluated using the Grading of Recommendations Assessment, Development, and Evaluation process. In instances where the evidence was not appropriate for Grading of Recommendations Assessment, Development, and Evaluation but there was consensus of significant clinical merit, key concept statements were developed using expert consensus. These guidelines are meant to be broadly applicable and should be viewed as the preferred, but not the only, approach to clinical scenarios.Clostridioides difficile infection occurs when the bacterium produces toxin that causes diarrhea and inflammation of the colon. These guidelines indicate the preferred approach to the management of adults with C. difficile infection and represent the official practice recommendations of the American College of Gastroenterology. The scientific evidence for these guidelines was evaluated using the Grading of Recommendations Assessment, Development, and Evaluation process. In instances where the evidence was not appropriate for Grading of Recommendations Assessment, Development, and Evaluation but there was consensus of significant clinical merit, key concept statements were developed using expert consensus. These guidelines are meant to be broadly applicable and should be viewed as the preferred, but not the only, approach to clinical scenarios. |
| Author | LaPlante, Kerry Kelly, Colleen R. Allegretti, Jessica R. Fischer, Monika Limketkai, Berkeley N. Stollman, Neil H. Stewart, David B. |
| AuthorAffiliation | Division of Gastroenterology, Alta Bates Summit Medical Center, East Bay Center for Digestive Health, Oakland, California, USA Division of Digestive Diseases, David Geffen School of Medicine at University of California Los Angeles, Los Angeles, California, USA Department of Pharmacy Practice, University of Rhode Island College of Pharmacy, Kingston, Rhode Island, USA Division of Gastroenterology, Warren Alpert Medical School of Brown University, Providence, Rhode Island, USA Department of Surgery, University of Arizona Health Sciences, Tucson, Arizona, USA Division of Gastroenterology, Indiana University, Indianapolis, Indiana, USA Division of Gastroenterology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA |
| AuthorAffiliation_xml | – name: Division of Digestive Diseases, David Geffen School of Medicine at University of California Los Angeles, Los Angeles, California, USA – name: Division of Gastroenterology, Warren Alpert Medical School of Brown University, Providence, Rhode Island, USA – name: Department of Pharmacy Practice, University of Rhode Island College of Pharmacy, Kingston, Rhode Island, USA – name: Department of Surgery, University of Arizona Health Sciences, Tucson, Arizona, USA – name: Division of Gastroenterology, Alta Bates Summit Medical Center, East Bay Center for Digestive Health, Oakland, California, USA – name: Division of Gastroenterology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA – name: Division of Gastroenterology, Indiana University, Indianapolis, Indiana, USA |
| Author_xml | – sequence: 1 givenname: Colleen R. surname: Kelly fullname: Kelly, Colleen R. organization: Division of Gastroenterology, Warren Alpert Medical School of Brown University, Providence, Rhode Island, USA – sequence: 2 givenname: Monika surname: Fischer fullname: Fischer, Monika organization: Division of Gastroenterology, Indiana University, Indianapolis, Indiana, USA – sequence: 3 givenname: Jessica R. surname: Allegretti fullname: Allegretti, Jessica R. organization: Division of Gastroenterology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA – sequence: 4 givenname: Kerry surname: LaPlante fullname: LaPlante, Kerry organization: Department of Pharmacy Practice, University of Rhode Island College of Pharmacy, Kingston, Rhode Island, USA – sequence: 5 givenname: David B. surname: Stewart fullname: Stewart, David B. organization: Department of Surgery, University of Arizona Health Sciences, Tucson, Arizona, USA – sequence: 6 givenname: Berkeley N. surname: Limketkai fullname: Limketkai, Berkeley N. organization: Division of Digestive Diseases, David Geffen School of Medicine at University of California Los Angeles, Los Angeles, California, USA – sequence: 7 givenname: Neil H. surname: Stollman fullname: Stollman, Neil H. organization: Division of Gastroenterology, Alta Bates Summit Medical Center, East Bay Center for Digestive Health, Oakland, California, USA |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/34003176$$D View this record in MEDLINE/PubMed |
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| SubjectTerms | Anti-Bacterial Agents - therapeutic use Antibiotics Clostridioides difficile - isolation & purification Clostridium Infections - diagnosis Clostridium Infections - drug therapy Clostridium Infections - prevention & control Diarrhea - drug therapy Diarrhea - microbiology Diarrhea - prevention & control Disease prevention Gastroenterology Humans Infections Infectious diseases Inflammation - drug therapy Inflammation - microbiology Inflammation - prevention & control Inflammatory bowel disease Long term health care Probiotics Recurrence Risk factors |
| Title | ACG Clinical Guidelines: Prevention, Diagnosis, and Treatment of Clostridioides difficile Infections |
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