The Avon Longitudinal Study of Parents and Children (ALSPAC): an update on the enrolled sample of index children in 2019

The Avon Longitudinal Study of Parents and Children (ALSPAC) is a prospective population-based study. Initial recruitment of pregnant women took place in 1990-1992 and the health and development of the index children from these pregnancies and their family members have been followed ever since. The...

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Published in:Wellcome open research Vol. 4; p. 51
Main Authors: Northstone, Kate, Lewcock, Melanie, Groom, Alix, Boyd, Andy, Macleod, John, Timpson, Nicholas, Wells, Nicholas
Format: Journal Article
Language:English
Published: England Wellcome Trust Limited 2019
F1000 Research Limited
Wellcome
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ISSN:2398-502X, 2398-502X
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Abstract The Avon Longitudinal Study of Parents and Children (ALSPAC) is a prospective population-based study. Initial recruitment of pregnant women took place in 1990-1992 and the health and development of the index children from these pregnancies and their family members have been followed ever since. The eligible sampling frame was constructed retrospectively using linked recruitment and health service records. Additional offspring that were eligible to enrol in the study have been welcomed through major recruitment drives at the ages of 7 and 18 years; and through opportunistic contacts since the age of 7. This data note provides a status update on the recruitment of the index children since the age of 7 years with a focus on enrolment since the age of 18, which has not been previously described. A total of 913 additional G1 (the cohort of index children) participants have been enrolled in the study since the age of 7 years with 195 of these joining since the age of 18. This additional enrolment provides a baseline sample of 14,901 G1 participants who were alive at 1 year of age.
AbstractList The Avon Longitudinal Study of Parents and Children (ALSPAC) is a prospective population-based study. Initial recruitment of pregnant women took place in 1990-1992 and the health and development of the index children from these pregnancies and their family members have been followed ever since. The eligible sampling frame was constructed retrospectively using linked recruitment and health service records. Additional offspring that were eligible to enrol in the study have been welcomed through major recruitment drives at the ages of 7 and 18 years; and through opportunistic contacts since the age of 7. This data note provides a status update on the recruitment of the index children since the age of 7 years with a focus on enrolment since the age of 18, which has not been previously described. A total of 913 additional G1 (the cohort of index children) participants have been enrolled in the study since the age of 7 years with 195 of these joining since the age of 18. This additional enrolment provides a baseline sample of 14,901 G1 participants who were alive at 1 year of age.
The Avon Longitudinal Study of Parents and Children (ALSPAC) is a prospective population-based study. Initial recruitment of pregnant women took place in 1990-1992 and the health and development of the index children from these pregnancies and their family members have been followed ever since. The eligible sampling frame was constructed retrospectively using linked recruitment and health service records. Additional offspring that were eligible to enrol in the study have been welcomed through major recruitment drives at the ages of 7 and 18 years; and through opportunistic contacts since the age of 7. This data note provides a status update on the recruitment of the index children since the age of 7 years with a focus on enrolment since the age of 18, which has not been previously described. A total of 913 additional G1 (the cohort of index children) participants have been enrolled in the study since the age of 7 years with 195 of these joining since the age of 18. This additional enrolment provides a baseline sample of 14,901 G1 participants who were alive at 1 year of age.The Avon Longitudinal Study of Parents and Children (ALSPAC) is a prospective population-based study. Initial recruitment of pregnant women took place in 1990-1992 and the health and development of the index children from these pregnancies and their family members have been followed ever since. The eligible sampling frame was constructed retrospectively using linked recruitment and health service records. Additional offspring that were eligible to enrol in the study have been welcomed through major recruitment drives at the ages of 7 and 18 years; and through opportunistic contacts since the age of 7. This data note provides a status update on the recruitment of the index children since the age of 7 years with a focus on enrolment since the age of 18, which has not been previously described. A total of 913 additional G1 (the cohort of index children) participants have been enrolled in the study since the age of 7 years with 195 of these joining since the age of 18. This additional enrolment provides a baseline sample of 14,901 G1 participants who were alive at 1 year of age.
Author Wells, Nicholas
Lewcock, Melanie
Timpson, Nicholas
Boyd, Andy
Macleod, John
Northstone, Kate
Groom, Alix
Author_xml – sequence: 1
  givenname: Kate
  orcidid: 0000-0002-0602-1983
  surname: Northstone
  fullname: Northstone, Kate
– sequence: 2
  givenname: Melanie
  surname: Lewcock
  fullname: Lewcock, Melanie
– sequence: 3
  givenname: Alix
  surname: Groom
  fullname: Groom, Alix
– sequence: 4
  givenname: Andy
  orcidid: 0000-0002-8614-3728
  surname: Boyd
  fullname: Boyd, Andy
– sequence: 5
  givenname: John
  surname: Macleod
  fullname: Macleod, John
– sequence: 6
  givenname: Nicholas
  orcidid: 0000-0002-7141-9189
  surname: Timpson
  fullname: Timpson, Nicholas
– sequence: 7
  givenname: Nicholas
  orcidid: 0000-0002-8619-5499
  surname: Wells
  fullname: Wells, Nicholas
BackLink https://www.ncbi.nlm.nih.gov/pubmed/31020050$$D View this record in MEDLINE/PubMed
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Cites_doi 10.1093/ije/dys064
10.1093/ije/dys066
10.12688/wellcomeopenres.15087.1
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Copyright: © 2019 Northstone K et al. 2019
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Keywords birth cohort study
enrolment
ALSPAC
cohort profile
Children of the 90s
Language English
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References A Boyd (ref-1) 2013; 42
D Lawlor (ref-3) 2019; 4
A Fraser (ref-2) 2013; 42
References_xml – volume: 42
  start-page: 111-127
  year: 2013
  ident: ref-1
  article-title: Cohort Profile: the 'children of the 90s'--the index offspring of the Avon Longitudinal Study of Parents and Children.
  publication-title: Int J Epidemiol.
  doi: 10.1093/ije/dys064
– volume: 42
  start-page: 97-110
  year: 2013
  ident: ref-2
  article-title: Cohort Profile: the Avon Longitudinal Study of Parents and Children: ALSPAC mothers cohort.
  publication-title: Int J Epidemiol.
  doi: 10.1093/ije/dys066
– volume: 4
  start-page: 36
  year: 2019
  ident: ref-3
  article-title: The second generation of The Avon Longitudinal Study of Parents and Children (ALSPAC-G2): a cohort profile [version 1; referees: awaiting peer review].
  publication-title: Wellcome Open.
  doi: 10.12688/wellcomeopenres.15087.1
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SubjectTerms Age
Children & youth
Clinics
Cohort analysis
Data dictionaries
Data Note
Families & family life
Longitudinal studies
Pregnancy
Proposals
Womens health
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Title The Avon Longitudinal Study of Parents and Children (ALSPAC): an update on the enrolled sample of index children in 2019
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