Hydration of nitriles using a metal-ligand cooperative ruthenium pincer catalyst

Nitrile hydration provides access to amides that are important structural elements in organic chemistry. Here we report catalytic nitrile hydration using ruthenium catalysts based on a pincer scaffold with a dearomatized pyridine backbone. These complexes catalyze the nucleophilic addition of H 2 O...

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Bibliographic Details

Published in:	Chemical science (Cambridge) Vol. 1; no. 45; pp. 1647 - 1652
Main Authors:	Guo, Beibei, de Vries, Johannes G, Otten, Edwin
Format:	Journal Article
Language:	English
Published:	England Royal Society of Chemistry 07.12.2019
Subjects:	Additives Aliphatic compounds Amides Catalysts Chemistry Hydration Ligands Nitriles Organic chemistry Room temperature Ruthenium Structural members
ISSN:	2041-6520, 2041-6539
Online Access:	Get full text
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