Antihypertensive medications and risk for incident dementia and Alzheimer's disease: a meta-analysis of individual participant data from prospective cohort studies

Dementia is a major health concern for which prevention and treatment strategies remain elusive. Lowering high blood pressure with specific antihypertensive medications (AHMs) could reduce the burden of disease. We investigated whether specific AHM classes reduced the risk for dementia. We did a met...

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Bibliographic Details
Published in:	Lancet neurology Vol. 19; no. 1; pp. 61 - 70
Main Authors:	Ding, Jie, Davis-Plourde, Kendra L, Sedaghat, Sanaz, Tully, Phillip J, Wang, Wanmei, Phillips, Caroline, Pase, Matthew P, Himali, Jayandra J, Gwen Windham, B, Griswold, Michael, Gottesman, Rebecca, Mosley, Thomas H, White, Lon, Guðnason, Vilmundur, Debette, Stéphanie, Beiser, Alexa S, Seshadri, Sudha, Ikram, M Arfan, Meirelles, Osorio, Tzourio, Christophe, Launer, Lenore J
Format:	Journal Article
Language:	English
Published:	England Elsevier Ltd 01.01.2020 Elsevier Limited
Subjects:	Age Aged Aged, 80 and over Aging Alzheimer Disease - epidemiology Alzheimer's disease Antihypertensive Agents - therapeutic use Antihypertensives Blood pressure Brain research Cardiovascular disease Clinical trials Cognition & reasoning Cognitive ability Cohort analysis Cohort Studies Dementia Dementia - epidemiology Dementia disorders Disease prevention Diuretics Enzymes Female Humans Hypertension Incidence Male Meta-analysis Middle Aged Neurodegenerative diseases Observational Studies as Topic Prospective Studies Risk Systematic review
ISSN:	1474-4422, 1474-4465, 1474-4465
Online Access:	Get full text
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