Effect of Colonoscopy Screening on Risks of Colorectal Cancer and Related Death

In this randomized trial involving 84,585 participants in Poland, Norway, and Sweden, the risk of colorectal cancer at 10 years was lower among those invited to undergo screening colonoscopy than among those assigned to no screening.

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Bibliographic Details
Published in:The New England journal of medicine Vol. 387; no. 17; pp. 1547 - 1556
Main Authors: Bretthauer, Michael, Løberg, Magnus, Wieszczy, Paulina, Kalager, Mette, Emilsson, Louise, Garborg, Kjetil, Rupinski, Maciej, Dekker, Evelien, Spaander, Manon, Bugajski, Marek, Holme, Øyvind, Zauber, Ann G., Pilonis, Nastazja D., Mroz, Andrzej, Kuipers, Ernst J., Shi, Joy, Hernán, Miguel A., Adami, Hans-Olov, Regula, Jaroslaw, Hoff, Geir, Kaminski, Michal F.
Format: Journal Article
Language:English
Published: United States Massachusetts Medical Society 27.10.2022
Subjects:
Cancer
Clinical Medicine
Clinical Medicine General
Colonic Polyps - diagnosis
Colonic Polyps - epidemiology
Colonic Polyps - surgery
Colonoscopy
Colonoscopy - adverse effects
Colonoscopy - methods
Colonoscopy - statistics & numerical data
Colorectal cancer
Colorectal carcinoma
Colorectal Neoplasms - diagnosis
Colorectal Neoplasms - epidemiology
Colorectal Neoplasms - mortality
Death
Early Detection of Cancer - adverse effects
Early Detection of Cancer - methods
Early Detection of Cancer - statistics & numerical data
Endoscopy
Ethics
Europe - epidemiology
Feces
Female
Follow-Up Studies
Gastroenterology
Gastrointestinal Tract Cancer
Hematology
Humans
Male
Mass Screening - adverse effects
Mass Screening - methods
Mass Screening - statistics & numerical data
Medical screening
Middle Aged
Mortality
Odds Ratio
Oncology
Outpatient-Based Clinical Medicine
Polyps
Risk
Statistical analysis
Tumors
Europe
Poland
Sweden
Netherlands
Norway
ISSN:0028-4793, 1533-4406, 1533-4406
Online Access:Get full text
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Description
Summary:In this randomized trial involving 84,585 participants in Poland, Norway, and Sweden, the risk of colorectal cancer at 10 years was lower among those invited to undergo screening colonoscopy than among those assigned to no screening.
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ISSN:0028-4793
1533-4406
1533-4406
DOI:10.1056/NEJMoa2208375