Dementia prevention, intervention, and care: 2024 report of the Lancet standing Commission

Evidence is increasing and is now stronger than before that tackling the many risk factors for dementia that we modelled previously (ie, less education, hearing loss, hypertension, smoking, obesity, depression, physical inactivity, diabetes, excessive alcohol consumption [ie, >21 UK units, equiva...

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Published in:The Lancet (British edition) Vol. 404; no. 10452; pp. 572 - 628
Main Authors: Livingston, Gill, Huntley, Jonathan, Liu, Kathy Y, Costafreda, Sergi G, Selbæk, Geir, Alladi, Suvarna, Ames, David, Banerjee, Sube, Burns, Alistair, Brayne, Carol, Fox, Nick C, Ferri, Cleusa P, Gitlin, Laura N, Howard, Robert, Kales, Helen C, Kivimäki, Mika, Larson, Eric B, Nakasujja, Noeline, Rockwood, Kenneth, Samus, Quincy, Shirai, Kokoro, Singh-Manoux, Archana, Schneider, Lon S, Walsh, Sebastian, Yao, Yao, Sommerlad, Andrew, Mukadam, Naaheed
Format: Journal Article
Language:English
Published: England Elsevier Ltd 10.08.2024
Elsevier Limited
Subjects:
Air pollution
Alcohol
Alcohol use
Alzheimer's disease
Biomarkers
Blood pressure
Cholesterol
Cognition & reasoning
Dementia
Dementia - epidemiology
Dementia - prevention & control
Dementia - therapy
Dementia disorders
Diabetes
Diabetes mellitus
Disease prevention
Education
Head injuries
Health care
Hearing aids
Hearing loss
Humans
Hypertension
Intervention
Low density lipoprotein
Low income groups
Middle age
Noise levels
Noise reduction
Obesity
Outdoor air quality
Risk factors
Risk reduction
Smoking
Social interactions
Social isolation
Traumatic brain injury
Wage & price controls
ISSN:0140-6736, 1474-547X, 1474-547X
Online Access:Get full text
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Summary:Evidence is increasing and is now stronger than before that tackling the many risk factors for dementia that we modelled previously (ie, less education, hearing loss, hypertension, smoking, obesity, depression, physical inactivity, diabetes, excessive alcohol consumption [ie, >21 UK units, equivalent to >12 US units], traumatic brain injury [TBI], air pollution, and social isolation) reduces the risk of developing dementia. Use of hearing aids appears to be particularly effective in people with hearing loss and additional risk factors for dementia. Key messages Two new modifiable risk factors for dementia New evidence supports adding vision loss and high cholesterol as potentially modifiable risk factors for dementia to the 12 risk factors identified in our 2020 Lancet Commission (ie, less education, head injury, physical inactivity, smoking, excessive alcohol consumption, hypertension, obesity, diabetes, hearing loss, depression, infrequent social contact, and air pollution). Make hearing aids accessible for people with hearing loss and decrease harmful noise exposure to reduce hearing loss
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ISSN:0140-6736
1474-547X
1474-547X
DOI:10.1016/S0140-6736(24)01296-0