Natural Killer Cell Receptors and Ligands Are Associated With Markers of HIV-1 Persistence in Chronically Infected ART Suppressed Patients

The latent HIV-1 reservoir represents a major barrier to achieving a long-term antiretroviral therapy (ART)-free remission or cure for HIV-1. Natural Killer (NK) cells are innate immune cells that play a critical role in controlling viral infections and have been shown to be involved in preventing H...

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Bibliographic Details
Published in:	Frontiers in cellular and infection microbiology Vol. 12; p. 757846
Main Authors:	Ivison, Geoffrey T., Vendrame, Elena, Martínez-Colón, Giovanny J., Ranganath, Thanmayi, Vergara, Rosemary, Zhao, Nancy Q., Martin, Maureen P., Bendall, Sean C., Carrington, Mary, Cyktor, Joshua C., McMahon, Deborah K., Eron, Joseph, Jones, R. Brad, Mellors, John W., Bosch, Ronald J., Gandhi, Rajesh T., Holmes, Susan, Blish, Catherine A.
Format:	Journal Article
Language:	English
Published:	Switzerland Frontiers Media SA 10.02.2022 Frontiers Media S.A
Subjects:	Acquired immune deficiency syndrome AIDS Antibodies Antiretroviral therapy CD16 antigen CD58 antigen Cellular and Infection Microbiology Chronic infection Genetic analysis Heterozygotes Histocompatibility antigen HLA HIV HIV cure HIV Infections - drug therapy HIV latency HIV-1 Human immunodeficiency virus human immunodeficiency virus (HIV) Humans Immunoglobulin-like receptors Infections Killer cell immunoglobulin-like receptors Ligands natural killer cell receptor ligands Natural killer cells NKG2 antigen Peptides Peripheral blood Phenotypes Plasma Potassium channels (inwardly-rectifying) Receptors, Natural Killer Cell - metabolism Receptors, Natural Killer Cell - therapeutic use Remission Tumor necrosis factor-TNF Virus Latency United States > US natural killer cell receptor ligands natural killer cells human immunodeficiency virus (HIV) HIV latency HIV cure
ISSN:	2235-2988, 2235-2988
Online Access:	Get full text
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