Imaging Mass Spectrometry: Enabling a New Age of Discovery in Biology and Medicine Through Molecular Microscopy

Imaging mass spectrometry (IMS) has become a valuable tool for the production of molecular maps in samples ranging from solid inorganic materials to biologicals such as cells and tissues. The unique features of IMS are its ability to map a wide variety of different types of molecules, its superb mol...

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Bibliographic Details
Published in:Journal of the American Society for Mass Spectrometry Vol. 26; no. 6; pp. 850 - 852
Main Author: Caprioli, Richard M.
Format: Journal Article
Language:English
Published: New York Springer US 01.06.2015
Springer Nature B.V
Subjects:
Analytical Chemistry
Animals
Bioinformatics
Biology
Biotechnology
Brain - anatomy & histology
Chemistry
Chemistry and Materials Science
Focus: Imaging Mass Spectrometry: Account & Perspective
Humans
Inorganic materials
Mass spectrometry
Mass Spectrometry - methods
Medicine
Mice
Microscopy - methods
Molecular Imaging - methods
Organic Chemistry
Pathology - methods
Proteomics
Reagents
Scientific imaging
Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization - methods
Spectroscopy
Molecular microscopy
Mass spectrometry
Imaging
MALDI MS
ISSN:1044-0305, 1879-1123, 1879-1123
Online Access:Get full text
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Description
Summary:Imaging mass spectrometry (IMS) has become a valuable tool for the production of molecular maps in samples ranging from solid inorganic materials to biologicals such as cells and tissues. The unique features of IMS are its ability to map a wide variety of different types of molecules, its superb molecular specificity, and its potential for discovery since no target-specific reagents are needed. IMS has made significant contributions in biology and medicine and promises to be a next generation tool in anatomic pathology. Graphical Abstract ᅟ
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ISSN:1044-0305
1879-1123
1879-1123
DOI:10.1007/s13361-015-1108-z