Estimation of Genetic Correlation via Linkage Disequilibrium Score Regression and Genomic Restricted Maximum Likelihood

Genetic correlation is a key population parameter that describes the shared genetic architecture of complex traits and diseases. It can be estimated by current state-of-art methods, i.e., linkage disequilibrium score regression (LDSC) and genomic restricted maximum likelihood (GREML). The massively...

Full description

Saved in:

Bibliographic Details
Published in:	American journal of human genetics Vol. 102; no. 6; p. 1185
Main Authors:	Ni, Guiyan, Moser, Gerhard, Wray, Naomi R, Lee, S Hong
Format:	Journal Article
Language:	English
Published:	United States 07.06.2018
Subjects:	Adult Body Height - genetics Computer Simulation Databases, Genetic Genome, Human Genotype Haplotypes - genetics Humans Inheritance Patterns - genetics Likelihood Functions Linkage Disequilibrium - genetics Phenotype Polymorphism, Single Nucleotide - genetics Regression Analysis Schizophrenia - genetics biasedness genome-wide SNPs body mass index linkage disequilibrium score regression accuracy genetic correlation schizophrenia genomic restricted maximum likelihood SNP heritability height
ISSN:	1537-6605, 1537-6605
Online Access:	Get more information
Tags:	Add Tag No Tags, Be the first to tag this record!

Be the first to leave a comment!