Silencing microRNA-155 ameliorates experimental autoimmune encephalomyelitis

IFN-γ-producing Th1 and IL-17-producing Th17 cells are the key participants in various autoimmune diseases, including multiple sclerosis and its animal model, experimental autoimmune encephalomyelitis (EAE). Although both of these T cell subsets are known to be regulated by specific transcription fa...

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Bibliographische Detailangaben

Veröffentlicht in:	The Journal of immunology (1950) Jg. 187; H. 5; S. 2213
Hauptverfasser:	Murugaiyan, Gopal, Beynon, Vanessa, Mittal, Akanksha, Joller, Nicole, Weiner, Howard L
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	England 01.09.2011
Schlagworte:	Animals CD4-Positive T-Lymphocytes - immunology Encephalomyelitis, Autoimmune, Experimental - genetics Encephalomyelitis, Autoimmune, Experimental - immunology Gene Silencing Inflammation - genetics Inflammation - immunology Mice Mice, Inbred C57BL Mice, Knockout MicroRNAs - genetics MicroRNAs - immunology Reverse Transcriptase Polymerase Chain Reaction T-Lymphocyte Subsets - immunology
ISSN:	1550-6606, 1550-6606
Online-Zugang:	Weitere Angaben
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