A dandelion polysaccharide and its selenium nanoparticles: Structure features and evaluation of anti-tumor activity in zebrafish models

In this study, an inulin fructan (TMP50-2) with moderate anti-tumor activity was obtained from dandelion. To further improve the anti-tumor activity of TMP50-2, a monodisperse and stable spherical nanoparticle (Tw-TMP-SeNP, 50 nm) was fabricated. Physico-chemical analysis revealed that TMP50-2 and T...

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Bibliographic Details
Published in:	Carbohydrate Polymers Vol. 270; p. 118365
Main Authors:	Zhang, Shaojie, Song, Ziteng, Shi, Lijuan, Zhou, Linan, Zhang, Jie, Cui, Jianlin, Li, Yuhao, Jin, Da-Qing, Ohizumi, Yasushi, Xu, Jing, Guo, Yuanqiang
Format:	Journal Article
Language:	English
Published:	England Elsevier Ltd 15.10.2021 Elsevier BV
Subjects:	A549 Cells angiogenesis Animals Anti-tumor activity antineoplastic activity Antineoplastic Agents Antineoplastic Agents - pharmacology Apoptosis Apoptosis - drug effects Cell Proliferation Cell Proliferation - drug effects Danio rerio dose response Fructan Fructans Fructans - chemistry Fructans - pharmacology HeLa Cells Hep G2 Cells Humans hydrogen Hydrogen Bonding inulin Nanoparticles Nanoparticles - chemistry Neoplasms Neoplasms - drug therapy Neoplasms - metabolism Neoplasms - pathology Polysaccharides Polysaccharides - chemistry Polysaccharides - pharmacology polysorbates Selenium Selenium - chemistry Selenium - pharmacology Selenium nanoparticles Taraxacum Taraxacum - chemistry Taraxacum mongolicum Hand.-Mazz Zebrafish Zebrafish Fructan Selenium nanoparticles Taraxacum mongolicum Hand.-Mazz Anti-tumor activity
ISSN:	0144-8617, 1879-1344, 1879-1344
Online Access:	Get full text
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