Phosphatidylinositolphosphate phosphatase activities and cancer

Signaling through the phosphoinositide 3-kinase pathways mediates the actions of a plethora of hormones, growth factors, cytokines, and neurotransmitters upon their target cells following receptor occupation. Overactivation of these pathways has been implicated in a number of pathologies, in particu...

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Veröffentlicht in:	Journal of lipid research Jg. 57; H. 2; S. 176 - 192
Hauptverfasser:	Rudge, Simon A, Wakelam, Michael J O
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States Elsevier 01.02.2016
Schlagworte:	cancer Gene Expression Regulation, Neoplastic Humans lipid kinases Lipid Metabolism - genetics Neoplasms - genetics Neoplasms - metabolism Neoplasms - pathology phosphatases/lipid Phosphatidylinositol 3-Kinases - genetics Phosphatidylinositol 3-Kinases - metabolism Phosphatidylinositol Phosphates - metabolism Phosphatidylinositols - metabolism phosphoinositide 3-kinase phosphoinositides Phosphoric Monoester Hydrolases - genetics Phosphoric Monoester Hydrolases - metabolism Signal Transduction phosphatases/lipid cancer lipid kinases phosphoinositide 3-kinase phosphoinositides
ISSN:	0022-2275, 1539-7262
Online-Zugang:	Volltext
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