Nutraceutic Potential of Bioactive Compounds of Eugenia dysenterica DC in Metabolic Alterations

The fruit and leaves of Eugenia dysenterica DC., locally known as cagaita, are rich in antioxidant glycosylated quercetin derivatives and phenolic compounds that have beneficial effects on diabetes mellitus, hypertension and general inflammation. We conducted a literature search to investigate the n...

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Published in:Molecules (Basel, Switzerland) Vol. 27; no. 8; p. 2477
Main Authors: Santana, Lidiani Figueiredo, Sasso, Sandramara, Aquino, Diana Figueiredo Santana, de Cássia Freitas, Karine, de Cássia Avellaneda Guimarães, Rita, Pott, Arnildo, do Nascimento, Valter Aragão, Bogo, Danielle, de Oliveira Figueiredo, Patrícia, Hiane, Priscila Aiko
Format: Journal Article
Language:English
Published: Switzerland MDPI AG 12.04.2022
MDPI
Subjects:
Antioxidants - pharmacology
Brazilian fruit
chronic diseases
Eugenia
Fruits
Humans
Hypertension
Inflammation
inflammation mediators
Kinases
Lipids
Oxidation
Phenols
Plant Extracts
Plant Leaves
Review
Vitamin C
Vitamin E
Brazilian fruit
chronic diseases
inflammation mediators
ISSN:1420-3049, 1420-3049
Online Access:Get full text
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Summary:The fruit and leaves of Eugenia dysenterica DC., locally known as cagaita, are rich in antioxidant glycosylated quercetin derivatives and phenolic compounds that have beneficial effects on diabetes mellitus, hypertension and general inflammation. We conducted a literature search to investigate the nutraceutical potentials of these phenolic compounds for treating obesity, diabetes mellitus and intestinal inflammatory disease. The phenolic compounds in E. dysenterica have demonstrated effects on carbohydrate metabolism, which can prevent the development of these chronic diseases and reduce LDL (low-density lipoprotein) cholesterol and hypertension. E. dysenterica also improves intestinal motility and microbiota and protects gastric mucosa, thereby preventing inflammation. However, studies are necessary to identify the mechanism by which E. dysenterica nutraceutical compounds act on such pathological processes to support future research.
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ISSN:1420-3049
1420-3049
DOI:10.3390/molecules27082477