Excitation and Inhibition Imbalance in Rett Syndrome

A loss of the excitation/inhibition (E/I) balance in the neural circuit has emerged as a common neuropathological feature in many neurodevelopmental disorders. Rett syndrome (RTT), a prevalent neurodevelopmental disorder that affects 1:10,000–15,000 women globally, is caused by loss-of-function muta...

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Bibliographic Details
Published in:	Frontiers in neuroscience Vol. 16; p. 825063
Main Author:	Li, Wei
Format:	Journal Article
Language:	English
Published:	Switzerland Frontiers Research Foundation 18.02.2022 Frontiers Media S.A
Subjects:	Autism Brain research Convulsions & seizures Coordination excitation/inhibition balance Hyperactivity MeCP2 MeCP2 protein Methyl-CpG binding protein Mutation neurodevelopmental disorder Neurodevelopmental disorders Neuroscience Pathogenesis Rett syndrome Rodents Seizures synaptic transmission MeCP2 synaptic transmission excitation/inhibition balance neurodevelopmental disorder Rett syndrome
ISSN:	1662-453X, 1662-4548, 1662-453X
Online Access:	Get full text
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