Synthesis of Functionalized Cannabilactones

A new approach to synthesize cannabilactones using Suzuki cross-coupling reaction followed by one-step demethylation-cyclization is presented. The two key cannabilactone prototypes AM1710 and AM1714 were obtained selectively in high overall yields and in a lesser number of synthetic steps when compa...

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Bibliographic Details

Published in:	Molecules (Basel, Switzerland) Vol. 25; no. 3; p. 684
Main Authors:	Liu, Yingpeng, Ho, Thanh C., Baradwan, Mohammed, Pascual Lopez-Alberca, Maria, Iliopoulos-Tsoutsouvas, Christos, Nikas, Spyros P., Makriyannis, Alexandros
Format:	Journal Article
Language:	English
Published:	Switzerland MDPI AG 06.02.2020 MDPI
Subjects:	Acids cannabilactones cannabinoids Cannabinoids - chemical synthesis cb2 selective ligands Chromones - chemical synthesis Pain suzuki cross-coupling Tetrahydrocannabinol THC cannabilactones cannabinoids CB2 selective ligands Suzuki cross-coupling
ISSN:	1420-3049, 1420-3049
Online Access:	Get full text
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