Important Flavonoids and Their Role as a Therapeutic Agent

Flavonoids are phytochemical compounds present in many plants, fruits, vegetables, and leaves, with potential applications in medicinal chemistry. Flavonoids possess a number of medicinal benefits, including anticancer, antioxidant, anti-inflammatory, and antiviral properties. They also have neuropr...

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Vydáno v:	Molecules (Basel, Switzerland) Ročník 25; číslo 22; s. 5243
Hlavní autoři:	Ullah, Asad, Munir, Sidra, Badshah, Syed Lal, Khan, Noreen, Ghani, Lubna, Poulson, Benjamin Gabriel, Emwas, Abdul-Hamid, Jaremko, Mariusz
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	Switzerland MDPI AG 11.11.2020 MDPI
Témata:	Alzheimer Disease - drug therapy Alzheimer Disease - prevention & control Angiogenesis Animals Anti-Inflammatory Agents - chemistry Anti-Inflammatory Agents - pharmacology Antifungal Agents - chemistry Antifungal Agents - pharmacology Antimalarials - chemistry Antimalarials - pharmacology Antineoplastic Agents - chemistry Antineoplastic Agents - pharmacology Antioxidants Antioxidants - chemistry Antioxidants - pharmacology antioxidative Antiviral Agents - chemistry Antiviral Agents - pharmacology Antiviral drugs Breast cancer Cancer therapies Cardiovascular System - drug effects Cell cycle Cell growth Colorectal cancer Cytotoxicity Drug dosages Flavonoids Flavonoids - chemistry Flavonoids - economics Flavonoids - pharmacology Fruits Humans Hypoglycemic Agents - chemistry Hypoglycemic Agents - pharmacology Kinases Liver cancer Metabolism Metabolites Mice Nanoparticles Nervous System - drug effects Neurons - drug effects neuroprotective Neuroprotective Agents - chemistry Neuroprotective Agents - pharmacology Phytochemicals Plant Extracts - pharmacology Plant Leaves - chemistry Plants - chemistry Polyphenols Polyphenols - chemistry Polyphenols - pharmacology quercetin Quercetin - chemistry Quercetin - pharmacology Rats Rats, Sprague-Dawley Rats, Wistar Review Stroke - drug therapy Stroke - prevention & control Vascular endothelial growth factor polyphenols quercetin antioxidative flavonoids neuroprotective
ISSN:	1420-3049, 1420-3049
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Popis
Shrnutí:	Flavonoids are phytochemical compounds present in many plants, fruits, vegetables, and leaves, with potential applications in medicinal chemistry. Flavonoids possess a number of medicinal benefits, including anticancer, antioxidant, anti-inflammatory, and antiviral properties. They also have neuroprotective and cardio-protective effects. These biological activities depend upon the type of flavonoid, its (possible) mode of action, and its bioavailability. These cost-effective medicinal components have significant biological activities, and their effectiveness has been proved for a variety of diseases. The most recent work is focused on their isolation, synthesis of their analogs, and their effects on human health using a variety of techniques and animal models. Thousands of flavonoids have been successfully isolated, and this number increases steadily. We have therefore made an effort to summarize the isolated flavonoids with useful activities in order to gain a better understanding of their effects on human health.
Bibliografie:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 14 ObjectType-Review-3 content type line 23
ISSN:	1420-3049 1420-3049
DOI:	10.3390/molecules25225243