Effect of intracameral air injection during Ahmed glaucoma valve implantation on hypertensive phase

The purpose of this study was to evaluate the difference in the incidence of the hypertensive phase (HP) between Ahmed glaucoma valve (AGV) patients who received intracameral air injection and those who did not. A total of 78 patients who underwent AGV surgery between January 1, 2016 and June 30, 20...

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Bibliographic Details
Published in:Scientific reports Vol. 15; no. 1; pp. 2738 - 8
Main Authors: Kim, Sunghyun, Kwon, Yoonsung, Lee, Jong Yeon
Format: Journal Article
Language:English
Published: London Nature Publishing Group UK 21.01.2025
Nature Publishing Group
Nature Portfolio
Subjects:
692/699/3161/3169/3170
692/699/3161/3172
Aged
Ahmed glaucoma valve
Air
Female
Glaucoma
Glaucoma - physiopathology
Glaucoma - surgery
Glaucoma drainage implant
Glaucoma Drainage Implants - adverse effects
Humanities and Social Sciences
Humans
Hypertension
Hypertensive phase
Injection
Intracameral air injection
Intraocular Pressure
Male
Middle Aged
multidisciplinary
Ocular Hypertension - etiology
Ocular Hypertension - prevention & control
Regression analysis
Retrospective Studies
Science
Science (multidisciplinary)
Surgery
Surgical outcomes
Glaucoma
Intracameral air injection
Glaucoma drainage implant
Ahmed glaucoma valve
Hypertensive phase
ISSN:2045-2322, 2045-2322
Online Access:Get full text
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Summary:The purpose of this study was to evaluate the difference in the incidence of the hypertensive phase (HP) between Ahmed glaucoma valve (AGV) patients who received intracameral air injection and those who did not. A total of 78 patients who underwent AGV surgery between January 1, 2016 and June 30, 2023 were included in this retrospective study. HP was defined as intraocular pressure (IOP) greater than 21 mmHg within the first 6 postoperative months. Among baseline characteristics, except for neovascular glaucoma and baseline IOP, there were no differences between the air injection and control groups. In the air injection group, the rate of HP was 19%, which was significantly lower than 49.1% in the control group ( p  = 0.017). In multivariate logistic regression analysis, baseline IOP had a significant positive correlation (OR: 1.120, p  = 0.026), while age and intracameral air injection had a significant negative correlation with the incidence of HP (OR: 0.938, p  = 0.028, OR: 0.142, p  = 0.029). Postoperative IOP at 1 year and surgical success rates were not different between the two groups. Intracameral air injection during AGV surgery can significantly reduce the risk of HP. Intracameral air injection can be a simple procedure in AGV surgery for reducing HP.
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ISSN:2045-2322
2045-2322
DOI:10.1038/s41598-025-87222-1