Marburg virus inclusions: A virus-induced microcompartment and interface to multivesicular bodies and the late endosomal compartment

Filovirus infection of target cells leads to the formation of virally induced cytoplasmic inclusions that contain viral nucleocapsids at different stages of maturation. While the role of the inclusions has been unclear since the identification of Marburg and Ebola viruses, it recently became clear t...

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Bibliographic Details
Published in:	European journal of cell biology Vol. 94; no. 7-9; pp. 323 - 331
Main Authors:	Dolnik, Olga, Stevermann, Lea, Kolesnikova, Larissa, Becker, Stephan
Format:	Journal Article
Language:	English
Published:	Germany Elsevier GmbH 01.07.2015
Subjects:	Alix Animals Cell Compartmentation - physiology Cell Line DNA-Binding Proteins - metabolism Endosomal Sorting Complexes Required for Transport - metabolism Endosomes - metabolism ESCRT Humans Inclusion Bodies, Viral - metabolism Inclusions Lamp-1 Late domain Lysosomal Membrane Proteins - metabolism Macrophages - virology Marburg virus Marburg Virus Disease - virology Marburgvirus - growth & development Multivesicular Bodies - physiology Nedd4 Nucleocapsid - biosynthesis Nucleocapsid - metabolism Nucleoprotein Nucleoproteins - metabolism Protein Transport Pseudopodia - metabolism ras GTPase-Activating Proteins - metabolism Transcription Factors - metabolism Virus Release - physiology Virus Replication - physiology Late domain Marburg virus ESCRT Alix Lamp-1 Nedd4 Nucleoprotein Inclusions
ISSN:	0171-9335, 1618-1298, 1618-1298
Online Access:	Get full text
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