Uptake Transporters of the SLC21, SLC22A, and SLC15A Families in Anticancer Therapy—Modulators of Cellular Entry or Pharmacokinetics?

Solute carrier transporters comprise a large family of uptake transporters involved in the transmembrane transport of a wide array of endogenous substrates such as hormones, nutrients, and metabolites as well as of clinically important drugs. Several cancer therapeutics, ranging from chemotherapeuti...

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Bibliographic Details
Published in:	Cancers Vol. 12; no. 8; p. 2263
Main Authors:	Brecht, Karin, Schäfer, Anima Magdalena, Meyer zu Schwabedissen, Henriette E.
Format:	Journal Article
Language:	English
Published:	Basel MDPI AG 12.08.2020 MDPI
Subjects:	ABC transporters Cancer Cancer therapies Care and treatment Carnitine Cell division Chemotherapy DNA topoisomerase inhibitors Drug metabolism Drug therapy Drugs Etiology Genes Hormones Kinases Liver cancer Metabolism Metabolites Nutrients Observations Organic anion transporting polypeptide Pharmaceuticals Pharmacokinetics Polypeptides Protein-tyrosine kinase Proteins Review Studies Thrombocytopenia Toxicity Tumor cells Tumors Switzerland
ISSN:	2072-6694, 2072-6694
Online Access:	Get full text
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