Indoleamine 2,3-dioxygenase-expressing mature human monocyte-derived dendritic cells expand potent autologous regulatory T cells

A comprehensive understanding of the complex, autologous cellular interactions and regulatory mechanisms that occur during normal dendritic cell (DC)-stimulated immune responses is critical to optimizing DC-based immunotherapy. We have found that mature, immunogenic human monocyte-derived DCs (moDCs...

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Bibliographic Details
Published in:	Blood Vol. 114; no. 3; p. 555
Main Authors:	Chung, David J, Rossi, Marco, Romano, Emanuela, Ghith, Jennifer, Yuan, Jianda, Munn, David H, Young, James W
Format:	Journal Article
Language:	English
Published:	United States 16.07.2009
Subjects:	Antigen Presentation Cell Proliferation Cells, Cultured Dendritic Cells - enzymology Dendritic Cells - immunology Humans Immunotherapy Indoleamine-Pyrrole 2,3,-Dioxygenase - genetics Indoleamine-Pyrrole 2,3,-Dioxygenase - immunology Monocytes T-Lymphocytes - cytology T-Lymphocytes - immunology T-Lymphocytes, Cytotoxic T-Lymphocytes, Regulatory - cytology T-Lymphocytes, Regulatory - immunology Up-Regulation - genetics
ISSN:	1528-0020, 1528-0020
Online Access:	Get more information
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