Inoculation of raccoons with a wild-type-based recombinant canine distemper virus results in viremia, lymphopenia, fever, and widespread histological lesions

Raccoons are naturally susceptible to canine distemper virus (CDV) infection and can be a potential source of spill-over events. CDV is a highly contagious morbillivirus that infects multiple species of carnivores and omnivores, resulting in severe and often fatal disease. Here, we used a recombinan...

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Bibliographic Details
Published in:	mSphere Vol. 8; no. 4; p. e0014423
Main Authors:	Roelofs, Dagmar, Schmitz, Katharina S., van Amerongen, Geert, Rijsbergen, Laurine C., Laksono, Brigitta M., Comvalius, Anouskha D., Nambulli, Sham, Rennick, Linda J., van Run, Peter, Duprex, W. Paul, van den Brand, Judith M. A., de Swart, Rik L., de Vries, Rory D.
Format:	Journal Article
Language:	English
Published:	United States American Society for Microbiology 24.08.2023
Subjects:	Animals Canine distemper canine distemper virus Carnivores Central nervous system distemper Dogs Experiments Fever Flow cytometry Genomes Immune system Immunohistochemistry Infections Inoculation Lesions Leukocytes Lymphatic system Lymphocytes Lymphoid tissue Lymphopenia Measles morbillivirus Mortality Myeloid cells Nucleotide sequence Pathogenesis Procyonidae raccoon Species Variance analysis Viremia Viruses United States > US morbillivirus pathogenesis raccoon canine distemper virus distemper
ISSN:	2379-5042, 2379-5042
Online Access:	Get full text
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