Occurrence of the antidiabetic drug Metformin and its ultimate transformation product Guanylurea in several compartments of the aquatic cycle

In 2030, the World Health Organization estimates that more than 350million people will be diagnosed with diabetes. Consequently, Metformin – the biguanide drug of choice orally administered for diabetes type II – is anticipated to see a spike in production. Unlike many pharmaceutical drugs, Metformi...

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Bibliographic Details
Published in:	Environment international Vol. 70; pp. 203 - 212
Main Authors:	Trautwein, Christoph, Berset, Jean-Daniel, Wolschke, Hendrik, Kümmerer, Klaus
Format:	Journal Article
Language:	English
Published:	Oxford Elsevier Ltd 01.09.2014 Elsevier
Subjects:	Animal, plant and microbial ecology Applied ecology Applied sciences Bacteria Bacteria - metabolism Biological and medical sciences Biotransformation drinking Drinking water Drinking Water - analysis Drinking Water - microbiology Drugs Ecotoxicology, biological effects of pollution Emerging contaminants Environmental Monitoring Environmental pollutants toxicology Exact sciences and technology food chain Fresh water environment Fundamental and applied biological sciences. Psychology humans hydrologic cycle Hypoglycemic Agents - analysis Hypoglycemic Agents - metabolism Kinetics Lake Constance Lakes liquid chromatography Marine and brackish environment mass spectrometry Medical sciences Metformin Metformin - analysis Metformin - metabolism Natural water pollution noninsulin-dependent diabetes mellitus North Sea oceans oral administration people Pharmaceuticals Pollution Rivers Rivers - chemistry Rivers - microbiology screening Seawater sewage Sewage - chemistry Sewage - microbiology sewage treatment tap water Thiourea - analysis Toxicology Transformations Waste water Water Water Pollutants, Chemical - analysis Water Pollutants, Chemical - metabolism Water treatment and pollution World Health Organization Europe Germany ANE, North Sea Europe, Constance L Europe, Elbe R Lake Constance North Sea Drinking water Pollution Emerging contaminants Waste water Seawater Pharmaceuticals Drug Transformation Pollutant behavior Metabolite Cycle Trophic chain Hypoglycemic agent Water pollution Metformin Contaminant Public health Chemical contamination
ISSN:	0160-4120, 1873-6750, 1873-6750
Online Access:	Get full text
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