Corticosteroids in the management of lymphocytic hypophysitis: Case series

Background: The diagnosis of lymphocytic hypophysitis (LYH) is a clinical challenge. Medical management with steroids may result in complete resolution of the symptoms and radiological features. We report our approach to the diagnosis and treatment of LYH. Materials and Methods: Retrospective analys...

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Bibliographic Details
Published in:	Neurology India Vol. 66; no. 2; pp. 400 - 404
Main Authors:	Panigrahi, Manas, Kumari, Manoranjitha, Vooturi, Sudhindra
Format:	Journal Article
Language:	English
Published:	India Wolters Kluwer India Pvt. Ltd 01.03.2018 Medknow Publications and Media Pvt. Ltd Medknow Publications & Media Pvt. Ltd
Subjects:	Adrenal Cortex Hormones - therapeutic use Adult Autoimmune diseases Autoimmune Hypophysitis - diagnostic imaging Autoimmune Hypophysitis - drug therapy Autoimmune Hypophysitis - surgery Corticosteroid drugs Diagnosis Disease Management Dosage and administration Excision (Surgery) Female Histopathology Humans India Laboratories Magnetic Resonance Imaging Male Medical diagnosis Middle Aged Neurosurgery Neurosurgical Procedures - methods NMR Nuclear magnetic resonance Patients Pituitary gland Retrospective Studies Steroids Surgery Thyroid gland Tumors Young Adult India Corticosteroids lymphocytic hypophysitis surgical resection Key Message: Lymphocytic hypophysitis may present with the characteristic magnetic resonance imaging features of stalk involvement and a homogenous enhancement of the lesion after contrast administration. Medical management by using steroids may play an equally important role as the surgical management. A patient suffering from an autoimmune disease who presents with a sellar lesion should be suspected of having lymphocytic hypophysitis. Surgical resection is often advocated when optic nerve and/or chiasmal compression is detected and for lesions nonresponsive to medical management the presence of a normal sella with the stalk in the midline the presence of a dural tail outcome absent T1 bright spot surgical resection
ISSN:	0028-3886, 1998-4022
Online Access:	Get full text
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