TVB-EduPack—An Interactive Learning and Scripting Platform for The Virtual Brain

The Virtual Brain (TVB; thevirtualbrain.org) is a neuroinformatics platform for full brain network simulation based on individual anatomical connectivity data. The framework addresses clinical and neuroscientific questions by simulating multi-scale neural dynamics that range from local population ac...

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Published in:Frontiers in neuroinformatics Vol. 9; p. 27
Main Authors: Matzke, Henrik, Schirner, Michael, Vollbrecht, Daniel, Rothmeier, Simon, Llarena, Adalberto, Rojas, Raúl, Triebkorn, Paul, Domide, Lia, Mersmann, Jochen, Solodkin, Ana, Jirsa, Viktor K., McIntosh, Anthony Randal, Ritter, Petra
Format: Journal Article
Language:English
Published: Switzerland Frontiers Research Foundation 25.11.2015
Frontiers Media S.A
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ISSN:1662-5196, 1662-5196
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Summary:The Virtual Brain (TVB; thevirtualbrain.org) is a neuroinformatics platform for full brain network simulation based on individual anatomical connectivity data. The framework addresses clinical and neuroscientific questions by simulating multi-scale neural dynamics that range from local population activity to large-scale brain function and related macroscopic signals like electroencephalography and functional magnetic resonance imaging. TVB is equipped with a graphical and a command-line interface to create models that capture the characteristic biological variability to predict the brain activity of individual subjects. To enable researchers from various backgrounds a quick start into TVB and brain network modeling in general, we developed an educational module: TVB-EduPack. EduPack offers two educational functionalities that seamlessly integrate into TVB's graphical user interface (GUI): (i) interactive tutorials introduce GUI elements, guide through the basic mechanics of software usage and develop complex use-case scenarios; animations, videos and textual descriptions transport essential principles of computational neuroscience and brain modeling; (ii) an automatic script generator records model parameters and produces input files for TVB's Python programming interface; thereby, simulation configurations can be exported as scripts that allow flexible customization of the modeling process and self-defined batch- and post-processing applications while benefitting from the full power of the Python language and its toolboxes. This article covers the implementation of TVB-EduPack and its integration into TVB architecture. Like TVB, EduPack is an open source community project that lives from the participation and contribution of its users. TVB-EduPack can be obtained as part of TVB from thevirtualbrain.org.
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Reviewed by: Marc De Kamps, University of Leeds, UK; Chung-Chuan Lo, National Tsing Hua University, Taiwan
These authors have contributed equally to this work.
Edited by: Arjen Van Ooyen, VU University Amsterdam, Netherlands
ISSN:1662-5196
1662-5196
DOI:10.3389/fninf.2015.00027