Long Non-coding RNAs Associated With Neurodegeneration-Linked Genes Are Reduced in Parkinson’s Disease Patients

Transcriptome analysis has identified a plethora of long non-coding RNAs (lncRNAs) expressed in the human brain and associated with neurological diseases. However, whether lncRNAs expression levels correlate with Parkinson's disease (PD) pathogenesis remains unknown. Herein, we show that a numb...

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Bibliographic Details
Published in:	Frontiers in cellular neuroscience Vol. 13; p. 58
Main Authors:	Elkouris, Maximilianos, Kouroupi, Georgia, Vourvoukelis, Alexios, Papagiannakis, Nikolaos, Kaltezioti, Valeria, Matsas, Rebecca, Stefanis, Leonidas, Xilouri, Maria, Politis, Panagiotis K.
Format:	Journal Article
Language:	English
Published:	Switzerland Frontiers Research Foundation 22.02.2019 Frontiers Media S.A
Subjects:	alpha-synuclein Biomedical research Brain research Cardiovascular disease Cell differentiation Cerebellum Cerebrospinal fluid Dopamine receptors Exosomes Gene expression Genomes Ischemia Leukocytes (mononuclear) long-non coding RNAs LRRK2 LRRK2 protein Medical prognosis MicroRNAs Movement disorders Neurodegeneration Neurodegenerative diseases Neurogenesis Neurological diseases Neuroscience Neurosciences Non-coding RNA PARK7 protein Parkinson's disease Pathogenesis Peripheral blood mononuclear cells Pluripotency Protein synthesis Proteins PTEN-induced putative kinase Stem cells Studies Substantia Nigra Transcription Greece alpha-synuclein Substantia Nigra LRRK2 exosomes Parkinson’s disease long-non coding RNAs
ISSN:	1662-5102, 1662-5102
Online Access:	Get full text
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