The impact of residual varus alignment following total knee arthroplasty on patient outcome scores in a constitutional varus population

Following a total knee arthroplasty (TKA), restoration of the mechanical axis of the lower limb to a neutral position of 0° ± 3° is generally considered the standard of care. Little is known, however, regarding the impact of realignment defined according to the patient's physiologic anatomy on...

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Veröffentlicht in:The knee Jg. 25; H. 6; S. 1278 - 1282
Hauptverfasser: Lanting, Brent A., Williams, Harley A., Matlovich, Nicholas F., Vandekerckhove, Pieter-Jan, Teeter, Matthew G., Vasarhelyi, Edward M., Howard, James L., Somerville, Lyndsay E.
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Sprache:Englisch
Veröffentlicht: Netherlands Elsevier B.V 01.12.2018
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ISSN:0968-0160, 1873-5800, 1873-5800
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Abstract Following a total knee arthroplasty (TKA), restoration of the mechanical axis of the lower limb to a neutral position of 0° ± 3° is generally considered the standard of care. Little is known, however, regarding the impact of realignment defined according to the patient's physiologic anatomy on clinical outcome scores. The study included 67 knees with a mean age of 65.9 ± 8.3 years with unilateral osteoarthritis (OA) who underwent a primary unilateral TKA for medial end-stage OA. Patients were categorized based on post-operative limb alignment in one of two ways, either based on alignment relative to their contralateral, physiologic side (physiologic), or alignment relative to a neutral axis (neutral). Knee Society Score (KSS), Western Ontario & McMaster Universities Osteoarthritis Index (WOMAC), and the 12-Item Short Form Survey (SF-12) were compared between the two groups. WOMAC Total and subscale scores improved for both groups between the pre- and post-operative time points. SF-12 scores were comparable post-operatively between the groups. WOMAC and KSS total and subscale scores were slightly greater post-operatively in the group not aligned according to their physiologic anatomy (neutral). However, none of these differences reached a level of significance. Post-operatively, residual varus and neutral limb alignment lead to comparable clinical outcome scores. In a constitutional varus population with medial end-stage OA, aligning the lower limb during a TKA to a neutral position rather than the patient's native anatomy does not negatively impact self-reported patient outcome scores at the one and two-year time points.
AbstractList Following a total knee arthroplasty (TKA), restoration of the mechanical axis of the lower limb to a neutral position of 0° ± 3° is generally considered the standard of care. Little is known, however, regarding the impact of realignment defined according to the patient's physiologic anatomy on clinical outcome scores. The study included 67 knees with a mean age of 65.9 ± 8.3 years with unilateral osteoarthritis (OA) who underwent a primary unilateral TKA for medial end-stage OA. Patients were categorized based on post-operative limb alignment in one of two ways, either based on alignment relative to their contralateral, physiologic side (physiologic), or alignment relative to a neutral axis (neutral). Knee Society Score (KSS), Western Ontario & McMaster Universities Osteoarthritis Index (WOMAC), and the 12-Item Short Form Survey (SF-12) were compared between the two groups. WOMAC Total and subscale scores improved for both groups between the pre- and post-operative time points. SF-12 scores were comparable post-operatively between the groups. WOMAC and KSS total and subscale scores were slightly greater post-operatively in the group not aligned according to their physiologic anatomy (neutral). However, none of these differences reached a level of significance. Post-operatively, residual varus and neutral limb alignment lead to comparable clinical outcome scores. In a constitutional varus population with medial end-stage OA, aligning the lower limb during a TKA to a neutral position rather than the patient's native anatomy does not negatively impact self-reported patient outcome scores at the one and two-year time points.
BackgroundFollowing a total knee arthroplasty (TKA), restoration of the mechanical axis of the lower limb to a neutral position of 0° ± 3° is generally considered the standard of care. Little is known, however, regarding the impact of realignment defined according to the patient's physiologic anatomy on clinical outcome scores.MethodsThe study included 67 knees with a mean age of 65.9 ± 8.3 years with unilateral osteoarthritis (OA) who underwent a primary unilateral TKA for medial end-stage OA. Patients were categorized based on post-operative limb alignment in one of two ways, either based on alignment relative to their contralateral, physiologic side (physiologic), or alignment relative to a neutral axis (neutral). Knee Society Score (KSS), Western Ontario & McMaster Universities Osteoarthritis Index (WOMAC), and the 12-Item Short Form Survey (SF-12) were compared between the two groups.ResultsWOMAC Total and subscale scores improved for both groups between the pre- and post-operative time points. SF-12 scores were comparable post-operatively between the groups. WOMAC and KSS total and subscale scores were slightly greater post-operatively in the group not aligned according to their physiologic anatomy (neutral). However, none of these differences reached a level of significance.ConclusionPost-operatively, residual varus and neutral limb alignment lead to comparable clinical outcome scores. In a constitutional varus population with medial end-stage OA, aligning the lower limb during a TKA to a neutral position rather than the patient's native anatomy does not negatively impact self-reported patient outcome scores at the one and two-year time points.
Following a total knee arthroplasty (TKA), restoration of the mechanical axis of the lower limb to a neutral position of 0° ± 3° is generally considered the standard of care. Little is known, however, regarding the impact of realignment defined according to the patient's physiologic anatomy on clinical outcome scores.BACKGROUNDFollowing a total knee arthroplasty (TKA), restoration of the mechanical axis of the lower limb to a neutral position of 0° ± 3° is generally considered the standard of care. Little is known, however, regarding the impact of realignment defined according to the patient's physiologic anatomy on clinical outcome scores.The study included 67 knees with a mean age of 65.9 ± 8.3 years with unilateral osteoarthritis (OA) who underwent a primary unilateral TKA for medial end-stage OA. Patients were categorized based on post-operative limb alignment in one of two ways, either based on alignment relative to their contralateral, physiologic side (physiologic), or alignment relative to a neutral axis (neutral). Knee Society Score (KSS), Western Ontario & McMaster Universities Osteoarthritis Index (WOMAC), and the 12-Item Short Form Survey (SF-12) were compared between the two groups.METHODSThe study included 67 knees with a mean age of 65.9 ± 8.3 years with unilateral osteoarthritis (OA) who underwent a primary unilateral TKA for medial end-stage OA. Patients were categorized based on post-operative limb alignment in one of two ways, either based on alignment relative to their contralateral, physiologic side (physiologic), or alignment relative to a neutral axis (neutral). Knee Society Score (KSS), Western Ontario & McMaster Universities Osteoarthritis Index (WOMAC), and the 12-Item Short Form Survey (SF-12) were compared between the two groups.WOMAC Total and subscale scores improved for both groups between the pre- and post-operative time points. SF-12 scores were comparable post-operatively between the groups. WOMAC and KSS total and subscale scores were slightly greater post-operatively in the group not aligned according to their physiologic anatomy (neutral). However, none of these differences reached a level of significance.RESULTSWOMAC Total and subscale scores improved for both groups between the pre- and post-operative time points. SF-12 scores were comparable post-operatively between the groups. WOMAC and KSS total and subscale scores were slightly greater post-operatively in the group not aligned according to their physiologic anatomy (neutral). However, none of these differences reached a level of significance.Post-operatively, residual varus and neutral limb alignment lead to comparable clinical outcome scores. In a constitutional varus population with medial end-stage OA, aligning the lower limb during a TKA to a neutral position rather than the patient's native anatomy does not negatively impact self-reported patient outcome scores at the one and two-year time points.CONCLUSIONPost-operatively, residual varus and neutral limb alignment lead to comparable clinical outcome scores. In a constitutional varus population with medial end-stage OA, aligning the lower limb during a TKA to a neutral position rather than the patient's native anatomy does not negatively impact self-reported patient outcome scores at the one and two-year time points.
AbstractBackgroundFollowing a total knee arthroplasty (TKA), restoration of the mechanical axis of the lower limb to a neutral position of 0° ± 3° is generally considered the standard of care. Little is known, however, regarding the impact of realignment defined according to the patient's physiologic anatomy on clinical outcome scores. MethodsThe study included 67 knees with a mean age of 65.9 ± 8.3 years with unilateral osteoarthritis (OA) who underwent a primary unilateral TKA for medial end-stage OA. Patients were categorized based on post-operative limb alignment in one of two ways, either based on alignment relative to their contralateral, physiologic side (physiologic), or alignment relative to a neutral axis (neutral). Knee Society Score (KSS), Western Ontario & McMaster Universities Osteoarthritis Index (WOMAC), and the 12-Item Short Form Survey (SF-12) were compared between the two groups. ResultsWOMAC Total and subscale scores improved for both groups between the pre- and post-operative time points. SF-12 scores were comparable post-operatively between the groups. WOMAC and KSS total and subscale scores were slightly greater post-operatively in the group not aligned according to their physiologic anatomy (neutral). However, none of these differences reached a level of significance. ConclusionPost-operatively, residual varus and neutral limb alignment lead to comparable clinical outcome scores. In a constitutional varus population with medial end-stage OA, aligning the lower limb during a TKA to a neutral position rather than the patient's native anatomy does not negatively impact self-reported patient outcome scores at the one and two-year time points.
Author Vasarhelyi, Edward M.
Lanting, Brent A.
Teeter, Matthew G.
Somerville, Lyndsay E.
Vandekerckhove, Pieter-Jan
Williams, Harley A.
Matlovich, Nicholas F.
Howard, James L.
Author_xml – sequence: 1
  givenname: Brent A.
  surname: Lanting
  fullname: Lanting, Brent A.
  organization: Department of Surgery, Division of Orthopaedic Surgery, Schulich School of Medicine & Dentistry, Western University & London Health Sciences Centre, University Campus, 339 Windermere Road, London, ON N6A 5A5, Canada
– sequence: 2
  givenname: Harley A.
  surname: Williams
  fullname: Williams, Harley A.
  email: harley.williams@lhsc.on.ca
  organization: Robarts Research Institute, Western University, 1151 Richmond Street, London, ON N6A 5B7, Canada
– sequence: 3
  givenname: Nicholas F.
  surname: Matlovich
  fullname: Matlovich, Nicholas F.
  organization: Department of Surgery, Division of Orthopaedic Surgery, Bluewater Health, 89 Norman Street, Sarnia, ON N7T 6S3, Canada
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  givenname: Pieter-Jan
  surname: Vandekerckhove
  fullname: Vandekerckhove, Pieter-Jan
  organization: Department of Surgery, Division of Orthopaedic Surgery, AZ Sint-Jan Brugge, Ruddershove10, 8000 Bruges, Belgium
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  givenname: Matthew G.
  surname: Teeter
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  organization: Department of Surgery, Division of Orthopaedic Surgery, Schulich School of Medicine & Dentistry, Western University & London Health Sciences Centre, University Campus, 339 Windermere Road, London, ON N6A 5A5, Canada
– sequence: 6
  givenname: Edward M.
  surname: Vasarhelyi
  fullname: Vasarhelyi, Edward M.
  organization: Department of Surgery, Division of Orthopaedic Surgery, Schulich School of Medicine & Dentistry, Western University & London Health Sciences Centre, University Campus, 339 Windermere Road, London, ON N6A 5A5, Canada
– sequence: 7
  givenname: James L.
  surname: Howard
  fullname: Howard, James L.
  organization: Department of Surgery, Division of Orthopaedic Surgery, Schulich School of Medicine & Dentistry, Western University & London Health Sciences Centre, University Campus, 339 Windermere Road, London, ON N6A 5A5, Canada
– sequence: 8
  givenname: Lyndsay E.
  surname: Somerville
  fullname: Somerville, Lyndsay E.
  organization: Department of Surgery, Division of Orthopaedic Surgery, Schulich School of Medicine & Dentistry, Western University & London Health Sciences Centre, University Campus, 339 Windermere Road, London, ON N6A 5A5, Canada
BackLink https://www.ncbi.nlm.nih.gov/pubmed/30314879$$D View this record in MEDLINE/PubMed
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CitedBy_id crossref_primary_10_1002_jeo2_70165
crossref_primary_10_1111_ans_18050
crossref_primary_10_1007_s43465_023_01016_z
crossref_primary_10_1186_s42836_022_00153_4
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Issue 6
Keywords Knee
Constitutional varus
Osteoarthritis
Clinical outcomes
Language English
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Snippet Following a total knee arthroplasty (TKA), restoration of the mechanical axis of the lower limb to a neutral position of 0° ± 3° is generally considered the...
AbstractBackgroundFollowing a total knee arthroplasty (TKA), restoration of the mechanical axis of the lower limb to a neutral position of 0° ± 3° is generally...
BackgroundFollowing a total knee arthroplasty (TKA), restoration of the mechanical axis of the lower limb to a neutral position of 0° ± 3° is generally...
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SubjectTerms Aged
Anatomy
Arthritis
Arthroplasty (knee)
Arthroplasty, Replacement, Knee - adverse effects
Arthroplasty, Replacement, Knee - methods
Bias
Biomechanics
Clinical outcomes
Constitutional varus
Design
Female
Genu Varum - surgery
Humans
Joint surgery
Knee
Knee Joint - surgery
Knee Prosthesis - adverse effects
Male
Middle Aged
Orthopedics
Osteoarthritis
Osteoarthritis, Knee - surgery
Patient Reported Outcome Measures
Patients
Polyethylene
Studies
Surgeons
Title The impact of residual varus alignment following total knee arthroplasty on patient outcome scores in a constitutional varus population
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https://www.ncbi.nlm.nih.gov/pubmed/30314879
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Volume 25
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