The Subgingival Microbiome of Periodontal Pockets With Different Probing Depths in Chronic and Aggressive Periodontitis: A Pilot Study
Periodontitis is a kind of infectious disease initiated by colonization of subgingival periodontal pathogens, which cause destruction of tooth-supporting tissues, and is a predominant threat to oral health as the most common cause of loss of teeth. The aim of this pilot study was to characterize the...
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| Vydané v: | Frontiers in cellular and infection microbiology Ročník 8; s. 124 |
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| Hlavní autori: | , , , , , |
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Frontiers Media SA
01.05.2018
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| Abstract | Periodontitis is a kind of infectious disease initiated by colonization of subgingival periodontal pathogens, which cause destruction of tooth-supporting tissues, and is a predominant threat to oral health as the most common cause of loss of teeth. The aim of this pilot study was to characterize the subgingival bacterial biodiversity of periodontal pockets with different probing depths in patients with different forms of periodontitis. Twenty-one subgingival plaque samples were collected from three patients with chronic periodontitis (ChP), three patients with aggressive periodontitis (AgP) and three periodontally healthy subjects (PH). Each patient with periodontitis was sampled at three sites, at different probing depths (PDs, one each at 4 mm, 5-6 mm, and ≥ 7 mm). Using 16S rRNA gene high-throughput sequencing and bioinformatic analysis, we found that subgingival communities in health and periodontitis samples largely differed. Meanwhile,
, and
increased with the deepening of the pockets in ChP, whilst only
was negatively associated with PD. In AgP,
and
were positively associated with PD, while
, and
were negatively associated with PD. And among these two groups,
shifted differently. Moreover, in subgingival plaque, the unweighted UniFrac distances between samples from pockets with different PD in the same patients were significantly lower than those from pockets within the same PD category from different patients. This study demonstrated the shift of the subgingival microbiome in individual teeth sites during disease development. Within the limitation of the relative small sample size, this pilot study shed new light on the dynamic relationship between the extent of periodontal destruction and the subgingival microbiome. |
|---|---|
| AbstractList | Periodontitis is a kind of infectious disease initiated by colonization of subgingival periodontal pathogens, which cause destruction of tooth-supporting tissues, and is a predominant threat to oral health as the most common cause of loss of teeth. The aim of this pilot study was to characterize the subgingival bacterial biodiversity of periodontal pockets with different probing depths in patients with different forms of periodontitis. Twenty-one subgingival plaque samples were collected from three patients with chronic periodontitis (ChP), three patients with aggressive periodontitis (AgP) and three periodontally healthy subjects (PH). Each patient with periodontitis was sampled at three sites, at different probing depths (PDs, one each at 4 mm, 5–6 mm, and ≥ 7 mm). Using 16S rRNA gene high-throughput sequencing and bioinformatic analysis, we found that subgingival communities in health and periodontitis samples largely differed. Meanwhile, Acholeplasma, Fretibacterium, Porphyromonas, Peptococcus, Treponema_2, Defluviitaleaceae_UCG_011, Filifactor, and Mycoplasma increased with the deepening of the pockets in ChP, whilst only Corynebacterium was negatively associated with PD. In AgP, Corynebacterium and Klebsiella were positively associated with PD, while Serratia, Pseudoramibacter, Defluviitaleaceae_UCG_011, and Desulfobulbus were negatively associated with PD. And among these two groups, Corynebacterium shifted differently. Moreover, in subgingival plaque, the unweighted UniFrac distances between samples from pockets with different PD in the same patients were significantly lower than those from pockets within the same PD category from different patients. This study demonstrated the shift of the subgingival microbiome in individual teeth sites during disease development. Within the limitation of the relative small sample size, this pilot study shed new light on the dynamic relationship between the extent of periodontal destruction and the subgingival microbiome. Periodontitis is a kind of infectious disease initiated by colonization of subgingival periodontal pathogens, which cause destruction of tooth-supporting tissues, and is a predominant threat to oral health as the most common cause of loss of teeth. The aim of this pilot study was to characterize the subgingival bacterial biodiversity of periodontal pockets with different probing depths in patients with different forms of periodontitis. Twenty-one subgingival plaque samples were collected from three patients with chronic periodontitis (ChP), three patients with aggressive periodontitis (AgP) and three periodontally healthy subjects (PH). Each patient with periodontitis was sampled at three sites, at different probing depths (PDs, one each at 4 mm, 5-6 mm, and ≥ 7 mm). Using 16S rRNA gene high-throughput sequencing and bioinformatic analysis, we found that subgingival communities in health and periodontitis samples largely differed. Meanwhile, , and increased with the deepening of the pockets in ChP, whilst only was negatively associated with PD. In AgP, and were positively associated with PD, while , and were negatively associated with PD. And among these two groups, shifted differently. Moreover, in subgingival plaque, the unweighted UniFrac distances between samples from pockets with different PD in the same patients were significantly lower than those from pockets within the same PD category from different patients. This study demonstrated the shift of the subgingival microbiome in individual teeth sites during disease development. Within the limitation of the relative small sample size, this pilot study shed new light on the dynamic relationship between the extent of periodontal destruction and the subgingival microbiome. Periodontitis is a kind of infectious disease initiated by colonization of subgingival periodontal pathogens, which cause destruction of tooth-supporting tissues, and is a predominant threat to oral health as the most common cause of loss of teeth. The aim of this pilot study was to characterize the subgingival bacterial biodiversity of periodontal pockets with different probing depths in patients with different forms of periodontitis. Twenty-one subgingival plaque samples were collected from three patients with chronic periodontitis (ChP), three patients with aggressive periodontitis (AgP) and three periodontally healthy subjects (PH). Each patient with periodontitis was sampled at three sites, at different probing depths (PDs, one each at 4 mm, 5-6 mm, and ≥ 7 mm). Using 16S rRNA gene high-throughput sequencing and bioinformatic analysis, we found that subgingival communities in health and periodontitis samples largely differed. Meanwhile, Acholeplasma, Fretibacterium, Porphyromonas, Peptococcus, Treponema_2, Defluviitaleaceae_UCG_011, Filifactor, and Mycoplasma increased with the deepening of the pockets in ChP, whilst only Corynebacterium was negatively associated with PD. In AgP, Corynebacterium and Klebsiella were positively associated with PD, while Serratia, Pseudoramibacter, Defluviitaleaceae_UCG_011, and Desulfobulbus were negatively associated with PD. And among these two groups, Corynebacterium shifted differently. Moreover, in subgingival plaque, the unweighted UniFrac distances between samples from pockets with different PD in the same patients were significantly lower than those from pockets within the same PD category from different patients. This study demonstrated the shift of the subgingival microbiome in individual teeth sites during disease development. Within the limitation of the relative small sample size, this pilot study shed new light on the dynamic relationship between the extent of periodontal destruction and the subgingival microbiome.Periodontitis is a kind of infectious disease initiated by colonization of subgingival periodontal pathogens, which cause destruction of tooth-supporting tissues, and is a predominant threat to oral health as the most common cause of loss of teeth. The aim of this pilot study was to characterize the subgingival bacterial biodiversity of periodontal pockets with different probing depths in patients with different forms of periodontitis. Twenty-one subgingival plaque samples were collected from three patients with chronic periodontitis (ChP), three patients with aggressive periodontitis (AgP) and three periodontally healthy subjects (PH). Each patient with periodontitis was sampled at three sites, at different probing depths (PDs, one each at 4 mm, 5-6 mm, and ≥ 7 mm). Using 16S rRNA gene high-throughput sequencing and bioinformatic analysis, we found that subgingival communities in health and periodontitis samples largely differed. Meanwhile, Acholeplasma, Fretibacterium, Porphyromonas, Peptococcus, Treponema_2, Defluviitaleaceae_UCG_011, Filifactor, and Mycoplasma increased with the deepening of the pockets in ChP, whilst only Corynebacterium was negatively associated with PD. In AgP, Corynebacterium and Klebsiella were positively associated with PD, while Serratia, Pseudoramibacter, Defluviitaleaceae_UCG_011, and Desulfobulbus were negatively associated with PD. And among these two groups, Corynebacterium shifted differently. Moreover, in subgingival plaque, the unweighted UniFrac distances between samples from pockets with different PD in the same patients were significantly lower than those from pockets within the same PD category from different patients. This study demonstrated the shift of the subgingival microbiome in individual teeth sites during disease development. Within the limitation of the relative small sample size, this pilot study shed new light on the dynamic relationship between the extent of periodontal destruction and the subgingival microbiome. |
| Author | Nie, Yong Wu, Xiaolei Wei, Yiping Shi, Meng Hu, Wenjie Lu, Ruifang |
| AuthorAffiliation | 2 Laboratory of Environmental Microbiology, Department of Energy and Resources Engineering, College of Engineering, Peking University , Beijing , China 1 Department of Periodontology, Peking University School and Hospital of Stomatology, National Clinical Research Center for Oral Diseases, National Engineering Laboratory for Digital and Material Technology of Stomatology, Beijing Key Laboratory of Digital Stomatology , Beijing , China |
| AuthorAffiliation_xml | – name: 1 Department of Periodontology, Peking University School and Hospital of Stomatology, National Clinical Research Center for Oral Diseases, National Engineering Laboratory for Digital and Material Technology of Stomatology, Beijing Key Laboratory of Digital Stomatology , Beijing , China – name: 2 Laboratory of Environmental Microbiology, Department of Energy and Resources Engineering, College of Engineering, Peking University , Beijing , China |
| Author_xml | – sequence: 1 givenname: Meng surname: Shi fullname: Shi, Meng – sequence: 2 givenname: Yiping surname: Wei fullname: Wei, Yiping – sequence: 3 givenname: Wenjie surname: Hu fullname: Hu, Wenjie – sequence: 4 givenname: Yong surname: Nie fullname: Nie, Yong – sequence: 5 givenname: Xiaolei surname: Wu fullname: Wu, Xiaolei – sequence: 6 givenname: Ruifang surname: Lu fullname: Lu, Ruifang |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/29765908$$D View this record in MEDLINE/PubMed |
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| Cites_doi | 10.1128/JCM.43.8.3944-3955.2005 10.1093/bioinformatics/btr507 10.1111/jcpe.12811 10.1128/JCM.43.11.5721-5732.2005 10.1111/adj.12076 10.1038/ismej.2010.30 10.1034/j.1600-051X.2002.290708.x 10.1177/00220345540330040201 10.1038/ismej.2012.174 10.18632/oncotarget.12532 10.1128/IAI.42.2.659-667.1983 10.1177/0022034515583531 10.1016/j.archoralbio.2014.11.015 10.1034/j.1600-051x.2001.028005377.x 10.1038/srep01843 10.1902/jop.1984.55.9.516 10.1111/j.1600-051X.1992.tb00670.x 10.1038/ismej.2011.191 10.1111/j.1600-0757.2006.00191.x 10.1371/journal.pone.0037919 10.1111/j.1600-051X.1991.tb00070.x 10.1128/AEM.00062-07 10.1093/humrep/dex372 10.1111/j.1600-0757.2010.00353.x 10.1038/nmeth.f.303 10.1128/mBio.01926-14 10.1111/1462-2920.12502 10.1016/j.archoralbio.2012.02.003 10.1902/annals.1999.4.1.1 10.1111/j.1600-051X.1998.tb02419.x 10.1111/jcpe.12463 10.1371/journal.pone.0065520 10.1016/j.mimet.2014.06.005 10.1038/ismej.2014.28 |
| ContentType | Journal Article |
| Copyright | 2018. This work is licensed under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. Copyright © 2018 Shi, Wei, Hu, Nie, Wu and Lu. 2018 Shi, Wei, Hu, Nie, Wu and Lu |
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| Keywords | subgingival microbiome aggressive periodontitis 16S rDNA high-throughput nucleotide sequencing chronic periodontitis |
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| References | Li (B20) 2014; 8 Al-Harthi (B3) 2013; 58 Li (B19) 2015; 42 Park (B26) 2015; 94 Heller (B17) 2012; 57 Socransky (B29) 1998; 25 Caporaso (B7) 2010; 7 Armitage (B5) 2010; 53 Pérez-Chaparro (B27) 2018; 45 Socransky (B30) 1991; 18 Eick (B8) 2002; 29 Bik (B6) 2010; 4 Abusleme (B2) 2013; 7 Shi (B28) 2015; 6 Armitage (B4) 1999; 4 Xu (B34) 2015; 17 Mettraux (B24) 1984; 55 Griffen (B12) 2012; 6 Yuan (B35) 2018; 33 Haffajee (B15) 2006; 42 Aas (B1) 2005; 43 Kumar (B18) 2005; 43 Loesche (B22) 1983; 42 Feng (B9) 2015; 60 Tsuzukibashi (B31) 2014; 104 Han (B16) 2017; 8 Forscher (B10) 1954; 33 Haffajee (B14) 1992; 19 Wang (B32) 2013; 3 Magoč (B23) 2011; 27 Haffajee (B13) 2001; 28 Newman (B25) 2011 Wang (B33) 2007; 73 Liu (B21) 2012; 7 Ge (B11) 2013; 8 |
| References_xml | – volume: 43 start-page: 3944 year: 2005 ident: B18 article-title: Identification of candidate periodontal pathogens and beneficial species by quantitative 16S clonal analysis publication-title: J. Clin. Microbiol. doi: 10.1128/JCM.43.8.3944-3955.2005 – volume: 27 start-page: 2957 year: 2011 ident: B23 article-title: FLASH: fast length adjustment of short reads to improve genome assemblies publication-title: Bioinformatics doi: 10.1093/bioinformatics/btr507 – volume: 45 start-page: 26 year: 2018 ident: B27 article-title: Do different probing depths exhibit striking differences in microbial profiles? publication-title: J. Clin. Periodontol. doi: 10.1111/jcpe.12811 – volume: 43 start-page: 5721 year: 2005 ident: B1 article-title: Defining the normal bacterial flora of the oral cavity publication-title: J. Clin. Microbiol. doi: 10.1128/JCM.43.11.5721-5732.2005 – volume: 58 start-page: 274 year: 2013 ident: B3 article-title: The impact of periodontitis on oral health-related quality of life: a review of the evidence from observational studies publication-title: Aust. Dent. J. doi: 10.1111/adj.12076 – volume: 4 start-page: 962 year: 2010 ident: B6 article-title: Bacterial diversity in the oral cavity of ten healthy individuals publication-title: ISME J. doi: 10.1038/ismej.2010.30 – volume: 29 start-page: 638 year: 2002 ident: B8 article-title: Comparison of microbial cultivation and a commercial PCR based method fordetection of periodontopathogenic species in subgingival plaque samples publication-title: J. Clin. Periodontol. doi: 10.1034/j.1600-051X.2002.290708.x – volume: 33 start-page: 444 year: 1954 ident: B10 article-title: The pH of the periodontal pocket and the glycogen content of the adjacent tissue publication-title: J. Dent. Res. doi: 10.1177/00220345540330040201 – volume: 7 start-page: 1016 year: 2013 ident: B2 article-title: The subgingival microbiome in health and periodontitis and its relationship with community biomass and inflammation publication-title: ISME J. doi: 10.1038/ismej.2012.174 – volume: 8 start-page: 10609 year: 2017 ident: B16 article-title: The microbial community shifts of subgingival plaque in patients with generalized aggressive periodontitis following non-surgical periodontal therapy: a pilot study publication-title: Oncotarget doi: 10.18632/oncotarget.12532 – volume: 42 start-page: 659 year: 1983 ident: B22 article-title: Relationship between oxygen tension and subgingival bacterial flora in untreated human periodontal pockets publication-title: Infect. Immun. doi: 10.1128/IAI.42.2.659-667.1983 – volume: 94 start-page: 921 year: 2015 ident: B26 article-title: Pyrosequencing analysis of subgingival microbiota in distinct periodontal conditions publication-title: J. Dent. Res. doi: 10.1177/0022034515583531 – volume: 60 start-page: 400 year: 2015 ident: B9 article-title: Distribution of 8 periodontal microorganisms in family members of Chinese patients with aggressive periodontitis publication-title: Arch. Oral Biol. doi: 10.1016/j.archoralbio.2014.11.015 – volume: 28 start-page: 377 year: 2001 ident: B13 article-title: Relationship of cigarette smoking to the subgingival microbiota publication-title: J. Clin. Periodontol. doi: 10.1034/j.1600-051x.2001.028005377.x – volume: 3 start-page: 1843 year: 2013 ident: B32 article-title: Metagenomic sequencing reveals microbiota and its functional potential associated with periodontal disease publication-title: Sci. Rep. doi: 10.1038/srep01843 – volume: 55 start-page: 516 year: 1984 ident: B24 article-title: Oxygen tension (pO2) in untreated human periodontal pockets publication-title: J. Periodontol. doi: 10.1902/jop.1984.55.9.516 – volume: 19 start-page: 401 year: 1992 ident: B14 article-title: Subgingival temperature (I). relation to baseline clinical parameters publication-title: J. Clin. Periodontol. doi: 10.1111/j.1600-051X.1992.tb00670.x – volume: 6 start-page: 1176 year: 2012 ident: B12 article-title: Distinct and complex bacterial profiles in human periodontitis and health revealed by 16S pyrosequencing publication-title: ISME J. doi: 10.1038/ismej.2011.191 – volume: 42 start-page: 219 year: 2006 ident: B15 article-title: The effect of periodontal therapy on the composition of the subgingival microbiota publication-title: Periodontol doi: 10.1111/j.1600-0757.2006.00191.x – volume: 7 start-page: e37919 year: 2012 ident: B21 article-title: Deep sequencing of the oral microbiome reveals signatures of periodontal disease publication-title: PLoS ONE doi: 10.1371/journal.pone.0037919 – volume-title: Carranza's Clinical Periodontology. year: 2011 ident: B25 – volume: 18 start-page: 766 year: 1991 ident: B30 article-title: Relation of counts of microbial species to clinical status at the sampled site publication-title: J. Clin. Periodontol. doi: 10.1111/j.1600-051X.1991.tb00070.x – volume: 73 start-page: 5261 year: 2007 ident: B33 article-title: Naive Bayesian classifier for rapid assignment of rRNA sequences into the new bacterial taxonomy publication-title: Appl. Environ. Microbiol. doi: 10.1128/AEM.00062-07 – volume: 33 start-page: 607 year: 2018 ident: B35 article-title: Endometriosis induces gut microbiota alterations in mice publication-title: Hum. Reprod. doi: 10.1093/humrep/dex372 – volume: 53 start-page: 12 year: 2010 ident: B5 article-title: Comparison of the clinical features of chronic and aggressive periodontitis publication-title: Periodontology doi: 10.1111/j.1600-0757.2010.00353.x – volume: 7 start-page: 335 year: 2010 ident: B7 article-title: QIIME allows analysis of high-throughput community sequencing data publication-title: Nat. Methods doi: 10.1038/nmeth.f.303 – volume: 6 start-page: e01926 year: 2015 ident: B28 article-title: Dynamic changes in the subgingival microbiome and their potential for diagnosis and prognosis of periodontitis publication-title: MBio doi: 10.1128/mBio.01926-14 – volume: 17 start-page: 699 year: 2015 ident: B34 article-title: Oral cavity contains distinct niches with dynamic microbial communities publication-title: Environ. Microbiol. doi: 10.1111/1462-2920.12502 – volume: 57 start-page: 973 year: 2012 ident: B17 article-title: Subgingival microbial profiles of generalized aggressive and chronic periodontal diseases publication-title: Arch. Oral Biol. doi: 10.1016/j.archoralbio.2012.02.003 – volume: 4 start-page: 1 year: 1999 ident: B4 article-title: Development of a classification system for periodontal diseases and conditions publication-title: Ann. Periodontol. doi: 10.1902/annals.1999.4.1.1 – volume: 25 start-page: 134 year: 1998 ident: B29 article-title: Microbial complexes in subgingival plaque publication-title: J. Clin. Periodontol. doi: 10.1111/j.1600-051X.1998.tb02419.x – volume: 42 start-page: 1015 year: 2015 ident: B19 article-title: Oral microbiome in chinese patients with aggressive periodontitis and their family members publication-title: J. Clin. Periodontol. doi: 10.1111/jcpe.12463 – volume: 8 start-page: e65520 year: 2013 ident: B11 article-title: Oral microbiome of deep and shallow dental pockets in chronic periodontitis publication-title: PLoS ONE doi: 10.1371/journal.pone.0065520 – volume: 104 start-page: 67 year: 2014 ident: B31 article-title: A selective medium for the isolation of Corynebacterium species in oral cavities publication-title: J. Microbiol. Methods doi: 10.1016/j.mimet.2014.06.005 – volume: 8 start-page: 1879 year: 2014 ident: B20 article-title: Phylogenetic and functional gene structure shifts of the oral microbiomes in periodontitis patients publication-title: ISME J. doi: 10.1038/ismej.2014.28 |
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