Role played by Toll-like receptors 2 and 4 in lipoteichoic acid-induced lung inflammation and coagulation

The cell wall of Streptococcus pneumoniae consists of lipoteichoic acid (LTA), which is released when pneumococci are killed by either the host immune system or antibiotic treatment. Release of excessive amounts of LTA has been implicated in the toxic sequelae of severe gram-positive infection by vi...

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Vydáno v:	The Journal of infectious diseases Ročník 197; číslo 2; s. 245
Hlavní autoři:	Dessing, Mark C, Schouten, Marcel, Draing, Christian, Levi, Marcel, von Aulock, Sonja, van der Poll, Tom
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	United States 15.01.2008
Témata:	Animals Blood Coagulation - immunology Blood Coagulation - physiology Female Inflammation - immunology Inflammation - physiopathology Lipopolysaccharide Receptors - metabolism Lipopolysaccharides - immunology Lipopolysaccharides - pharmacology Lung - immunology Lung - physiopathology Male Mice Mice, Inbred C57BL Mice, Knockout Specific Pathogen-Free Organisms Streptococcus pneumoniae - immunology Streptococcus pneumoniae - pathogenicity Teichoic Acids - immunology Teichoic Acids - pharmacology Toll-Like Receptor 2 - metabolism Toll-Like Receptor 4 - metabolism
ISSN:	0022-1899
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