Connecting imaging mass spectrometry and magnetic resonance imaging-based anatomical atlases for automated anatomical interpretation and differential analysis

Imaging mass spectrometry (IMS) is a molecular imaging technology that can measure thousands of biomolecules concurrently without prior tagging, making it particularly suitable for exploratory research. However, the data size and dimensionality often makes thorough extraction of relevant information...

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Bibliographic Details
Published in:	Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics Vol. 1865; no. 7; pp. 967 - 977
Main Authors:	Verbeeck, Nico, Spraggins, Jeffrey M., Murphy, Monika J.M., Wang, Hui-dong, Deutch, Ariel Y., Caprioli, Richard M., Van de Plas, Raf
Format:	Journal Article
Language:	English
Published:	Netherlands Elsevier B.V 01.07.2017 Elsevier BV
Subjects:	Anatomical atlas animal models Animals biochemical compounds Brain Brain - anatomy & histology Brain - metabolism Brain - pathology FTICR MS image analysis Image Processing, Computer-Assisted Image Processing, Computer-Assisted - methods Imaging mass spectrometry Imaging, Three-Dimensional Imaging, Three-Dimensional - methods Ions Ions - metabolism Magnetic Resonance Imaging Magnetic Resonance Imaging - methods Male Mass Spectrometry Mass Spectrometry - methods Mice MRI Parkinson Disease Parkinson Disease - pathology Rat brain Rats Rats, Sprague-Dawley SBA PD AMBA MRI Imaging mass spectrometry t-SNE FTICR MS FTICR Rat brain PCA Anatomical atlas
ISSN:	1570-9639, 1878-1454
Online Access:	Get full text
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