Atypical Presentation of Antiphospholipid Syndrome: A Case Report

We report an atypical presentation of Antiphospholipid syndrome (APS) with concomitant subhyaloid hemorrhage, engorged and tortuous retinal veins, intraretinal hemorrhages, and cotton wool spots in a 38-year-old female. Medical treatment was preferred to any invasive treatment. The subhyaloid hemorr...

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Published in:Case reports in ophthalmology Vol. 5; no. 3; pp. 400 - 404
Main Authors: Mariotti, Cesare, Giovannini, Alfonso, Reibaldi, Michele, Saitta, Andrea, Viti, Francesca, Nicolai, Michele
Format: Journal Article
Language:English
Published: Basel, Switzerland S. Karger AG 26.11.2014
Karger Publishers
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ISSN:1663-2699, 1663-2699
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Abstract We report an atypical presentation of Antiphospholipid syndrome (APS) with concomitant subhyaloid hemorrhage, engorged and tortuous retinal veins, intraretinal hemorrhages, and cotton wool spots in a 38-year-old female. Medical treatment was preferred to any invasive treatment. The subhyaloid hemorrhage resolved spontaneously and the patient recovered a visual acuity of 20/20 in her right eye 3 months after the initial episode. A prompt diagnosis of this condition is fundamental to consider a systemic treatment to avoid any further thrombosis.
AbstractList We report an atypical presentation of Antiphospholipid syndrome (APS) with concomitant subhyaloid hemorrhage, engorged and tortuous retinal veins, intraretinal hemorrhages, and cotton wool spots in a 38-year-old female. Medical treatment was preferred to any invasive treatment. The subhyaloid hemorrhage resolved spontaneously and the patient recovered a visual acuity of 20/20 in her right eye 3 months after the initial episode. A prompt diagnosis of this condition is fundamental to consider a systemic treatment to avoid any further thrombosis.
We report an atypical presentation of Antiphospholipid syndrome (APS) with concomitant subhyaloid hemorrhage, engorged and tortuous retinal veins, intraretinal hemorrhages, and cotton wool spots in a 38-year-old female. Medical treatment was preferred to any invasive treatment. The subhyaloid hemorrhage resolved spontaneously and the patient recovered a visual acuity of 20/20 in her right eye 3 months after the initial episode. A prompt diagnosis of this condition is fundamental to consider a systemic treatment to avoid any further thrombosis.We report an atypical presentation of Antiphospholipid syndrome (APS) with concomitant subhyaloid hemorrhage, engorged and tortuous retinal veins, intraretinal hemorrhages, and cotton wool spots in a 38-year-old female. Medical treatment was preferred to any invasive treatment. The subhyaloid hemorrhage resolved spontaneously and the patient recovered a visual acuity of 20/20 in her right eye 3 months after the initial episode. A prompt diagnosis of this condition is fundamental to consider a systemic treatment to avoid any further thrombosis.
Author Nicolai, Michele
Giovannini, Alfonso
Reibaldi, Michele
Viti, Francesca
Mariotti, Cesare
Saitta, Andrea
AuthorAffiliation c Department of Ophthalmology University of Catania, Catania, Italy
b Department of Ophthalmology Ospedali Riuniti, Ancona, Italy
a Department of Ophthalmology Università Politecnica delle Marche, Italy
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Keywords Intraretinal hemorrhage
Antiphospholipid syndrome
Subhyaloid hemorrhage
Language English
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PublicationTitle Case reports in ophthalmology
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Cervera R, Boffa MC, Khamashta MA, et al: The Euro-Phospholipid project: epidemiology of the antiphospholipid syndrome in Europe. Lupus 2009;18:889-893.1967178810.1177/0961203309106832
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References_xml – reference: Boets EP, Chaar CG, Roday K, Keunen JE, Breedveld FC: Chorioretinopathy in primary antiphospholipid syndrome: a case report. Retina 1998;18:382-385.973018810.1097/00006982-199807000-00019
– reference: Asherson RA, Merry P, Acheson JF, et al: Antiphospholipid antibodies: a risk factor for occlusive ocular vascular disease in systemic lupus erythematosus and the ‘primary' antiphospholipid syndrome. Ann Rheum Dis 1989;48:358-361.263767810.1136/ard.48.5.358
– reference: Cervera R, Boffa MC, Khamashta MA, et al: The Euro-Phospholipid project: epidemiology of the antiphospholipid syndrome in Europe. Lupus 2009;18:889-893.1967178810.1177/0961203309106832
– reference: Miyakis S, Lockshin MD, Atsumi T, et al: International consensus statement on an update of the classification criteria for definite antiphospholipid syndrome (APS). J Thromb Haemost 2006;4:295-306.1642055410.1111/j.1538-7836.2006.01753.x
– reference: Demirci FY, Kucukkaya R, Akarcay K, et al: Ocular involvement in primary antiphospholipid syndrome. Ocular involvement in primary APS. Int Ophthalmol 1998;22:323-329.1093784510.1023/A:1006305705080
– reference: Leo-Kottler B, Klein R, Berg PA, et al: Ocular symptoms in association with antiphospholipid antibodies. Graefes Arch Clin Exp Ophthalmol 1998;236:658-668.978242610.1007/s004170050138
– reference: Wong RC, Favaloro EJ: Clinical features, diagnosis, and management of the antiphospholipid syndrome. Semin Thromb Hemost 2008;34:295-304.1872031110.1055/s-0028-1082275
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– ident: ref4
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SubjectTerms Antiphospholipid syndrome
Intraretinal hemorrhage
Published: November 2014
Subhyaloid hemorrhage
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