Atypical Presentation of Antiphospholipid Syndrome: A Case Report
We report an atypical presentation of Antiphospholipid syndrome (APS) with concomitant subhyaloid hemorrhage, engorged and tortuous retinal veins, intraretinal hemorrhages, and cotton wool spots in a 38-year-old female. Medical treatment was preferred to any invasive treatment. The subhyaloid hemorr...
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| Published in: | Case reports in ophthalmology Vol. 5; no. 3; pp. 400 - 404 |
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| Main Authors: | , , , , , |
| Format: | Journal Article |
| Language: | English |
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Basel, Switzerland
S. Karger AG
26.11.2014
Karger Publishers |
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| ISSN: | 1663-2699, 1663-2699 |
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| Abstract | We report an atypical presentation of Antiphospholipid syndrome (APS) with concomitant subhyaloid hemorrhage, engorged and tortuous retinal veins, intraretinal hemorrhages, and cotton wool spots in a 38-year-old female. Medical treatment was preferred to any invasive treatment. The subhyaloid hemorrhage resolved spontaneously and the patient recovered a visual acuity of 20/20 in her right eye 3 months after the initial episode. A prompt diagnosis of this condition is fundamental to consider a systemic treatment to avoid any further thrombosis. |
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| AbstractList | We report an atypical presentation of Antiphospholipid syndrome (APS) with concomitant subhyaloid hemorrhage, engorged and tortuous retinal veins, intraretinal hemorrhages, and cotton wool spots in a 38-year-old female. Medical treatment was preferred to any invasive treatment. The subhyaloid hemorrhage resolved spontaneously and the patient recovered a visual acuity of 20/20 in her right eye 3 months after the initial episode. A prompt diagnosis of this condition is fundamental to consider a systemic treatment to avoid any further thrombosis. We report an atypical presentation of Antiphospholipid syndrome (APS) with concomitant subhyaloid hemorrhage, engorged and tortuous retinal veins, intraretinal hemorrhages, and cotton wool spots in a 38-year-old female. Medical treatment was preferred to any invasive treatment. The subhyaloid hemorrhage resolved spontaneously and the patient recovered a visual acuity of 20/20 in her right eye 3 months after the initial episode. A prompt diagnosis of this condition is fundamental to consider a systemic treatment to avoid any further thrombosis.We report an atypical presentation of Antiphospholipid syndrome (APS) with concomitant subhyaloid hemorrhage, engorged and tortuous retinal veins, intraretinal hemorrhages, and cotton wool spots in a 38-year-old female. Medical treatment was preferred to any invasive treatment. The subhyaloid hemorrhage resolved spontaneously and the patient recovered a visual acuity of 20/20 in her right eye 3 months after the initial episode. A prompt diagnosis of this condition is fundamental to consider a systemic treatment to avoid any further thrombosis. |
| Author | Nicolai, Michele Giovannini, Alfonso Reibaldi, Michele Viti, Francesca Mariotti, Cesare Saitta, Andrea |
| AuthorAffiliation | c Department of Ophthalmology University of Catania, Catania, Italy b Department of Ophthalmology Ospedali Riuniti, Ancona, Italy a Department of Ophthalmology Università Politecnica delle Marche, Italy |
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| Keywords | Intraretinal hemorrhage Antiphospholipid syndrome Subhyaloid hemorrhage |
| Language | English |
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| References | Utz VM, Tang J: Ocular manifestations of the antiphospholipid syndrome Br J Ophthalmol 2011;95:454-459.2069355710.1136/bjo.2010.182857 Cervera R, Boffa MC, Khamashta MA, et al: The Euro-Phospholipid project: epidemiology of the antiphospholipid syndrome in Europe. Lupus 2009;18:889-893.1967178810.1177/0961203309106832 Miyakis S, Lockshin MD, Atsumi T, et al: International consensus statement on an update of the classification criteria for definite antiphospholipid syndrome (APS). J Thromb Haemost 2006;4:295-306.1642055410.1111/j.1538-7836.2006.01753.x Boets EP, Chaar CG, Roday K, Keunen JE, Breedveld FC: Chorioretinopathy in primary antiphospholipid syndrome: a case report. Retina 1998;18:382-385.973018810.1097/00006982-199807000-00019 Asherson RA, Merry P, Acheson JF, et al: Antiphospholipid antibodies: a risk factor for occlusive ocular vascular disease in systemic lupus erythematosus and the ‘primary' antiphospholipid syndrome. Ann Rheum Dis 1989;48:358-361.263767810.1136/ard.48.5.358 Demirci FY, Kucukkaya R, Akarcay K, et al: Ocular involvement in primary antiphospholipid syndrome. Ocular involvement in primary APS. Int Ophthalmol 1998;22:323-329.1093784510.1023/A:1006305705080 Wong RC, Favaloro EJ: Clinical features, diagnosis, and management of the antiphospholipid syndrome. Semin Thromb Hemost 2008;34:295-304.1872031110.1055/s-0028-1082275 Levine JS, Branch DW, Rauch J: The antiphospholipid syndrome. N Engl J Med 2002;346:752-763.1188273210.1056/NEJMra002974 Leo-Kottler B, Klein R, Berg PA, et al: Ocular symptoms in association with antiphospholipid antibodies. Graefes Arch Clin Exp Ophthalmol 1998;236:658-668.978242610.1007/s004170050138 ref8 ref7 ref9 ref4 ref3 ref6 ref5 ref2 ref1 |
| References_xml | – reference: Boets EP, Chaar CG, Roday K, Keunen JE, Breedveld FC: Chorioretinopathy in primary antiphospholipid syndrome: a case report. Retina 1998;18:382-385.973018810.1097/00006982-199807000-00019 – reference: Asherson RA, Merry P, Acheson JF, et al: Antiphospholipid antibodies: a risk factor for occlusive ocular vascular disease in systemic lupus erythematosus and the ‘primary' antiphospholipid syndrome. Ann Rheum Dis 1989;48:358-361.263767810.1136/ard.48.5.358 – reference: Cervera R, Boffa MC, Khamashta MA, et al: The Euro-Phospholipid project: epidemiology of the antiphospholipid syndrome in Europe. Lupus 2009;18:889-893.1967178810.1177/0961203309106832 – reference: Miyakis S, Lockshin MD, Atsumi T, et al: International consensus statement on an update of the classification criteria for definite antiphospholipid syndrome (APS). J Thromb Haemost 2006;4:295-306.1642055410.1111/j.1538-7836.2006.01753.x – reference: Demirci FY, Kucukkaya R, Akarcay K, et al: Ocular involvement in primary antiphospholipid syndrome. Ocular involvement in primary APS. Int Ophthalmol 1998;22:323-329.1093784510.1023/A:1006305705080 – reference: Leo-Kottler B, Klein R, Berg PA, et al: Ocular symptoms in association with antiphospholipid antibodies. Graefes Arch Clin Exp Ophthalmol 1998;236:658-668.978242610.1007/s004170050138 – reference: Wong RC, Favaloro EJ: Clinical features, diagnosis, and management of the antiphospholipid syndrome. Semin Thromb Hemost 2008;34:295-304.1872031110.1055/s-0028-1082275 – reference: Utz VM, Tang J: Ocular manifestations of the antiphospholipid syndrome Br J Ophthalmol 2011;95:454-459.2069355710.1136/bjo.2010.182857 – reference: Levine JS, Branch DW, Rauch J: The antiphospholipid syndrome. N Engl J Med 2002;346:752-763.1188273210.1056/NEJMra002974 – ident: ref7 doi: 10.1177/0961203309106832 – ident: ref2 doi: 10.1136/bjo.2010.182857 – ident: ref3 doi: 10.1055/s-0028-1082275 – ident: ref4 doi: 10.1056/NEJMra002974 – ident: ref8 doi: 10.1007/s004170050138 – ident: ref1 doi: 10.1111/j.1538-7836.2006.01753.x – ident: ref9 doi: 10.1097/00006982-199807000-00019 – ident: ref5 doi: 10.1136/ard.48.5.358 – ident: ref6 doi: 10.1023/A:1006305705080 |
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| SubjectTerms | Antiphospholipid syndrome Intraretinal hemorrhage Published: November 2014 Subhyaloid hemorrhage |
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| Title | Atypical Presentation of Antiphospholipid Syndrome: A Case Report |
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