A long noncoding RNA signature for ulcerative colitis identifies IFNG-AS1 as an enhancer of inflammation

High-throughput technologies revealed new categories of genes, including the long noncoding RNAs (lncRNAs), involved in the pathogenesis of human disease; however, the role of lncRNAs in the ulcerative colitis (UC) has not been evaluated. Gene expression profiling was used to develop lncRNA signatur...

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Veröffentlicht in:	American journal of physiology: Gastrointestinal and liver physiology Jg. 311; H. 3; S. G446 - G457
Hauptverfasser:	Padua, David, Mahurkar-Joshi, Swapna, Law, Ivy Ka Man, Polytarchou, Christos, Vu, John P, Pisegna, Joseph R, Shih, David, Iliopoulos, Dimitrios, Pothoulakis, Charalabos
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States 01.09.2016
Schlagworte:	Adult Aged Animals Case-Control Studies Colitis, Ulcerative - metabolism Female Gene Expression Regulation - physiology Humans Inflammation - metabolism Interferon-gamma - genetics Interferon-gamma - metabolism Interleukin-10 - genetics Interleukin-10 - metabolism Jurkat Cells Male Mice Mice, Inbred C57BL Mice, Knockout Middle Aged RNA, Long Noncoding - genetics RNA, Long Noncoding - metabolism RNA, Messenger - genetics RNA, Messenger - metabolism ulcerative colitis lncRNA inflammation inflammatory bowel disease interferon γ
ISSN:	1522-1547
Online-Zugang:	Weitere Angaben
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