TET2 mutation is an independent favorable prognostic factor in myelodysplastic syndromes (MDSs)

Oncogenic pathways underlying in the development of myelodysplastic syndromes (MDS) remain poorly characterized, but mutations of the ten-eleven translocation 2 (TET2) gene are frequently observed. In the present work, we evaluated the prognostic impact of TET2 mutations in MDS. Frameshift, nonsense...

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Vydáno v:	Blood Ročník 114; číslo 15; s. 3285
Hlavní autoři:	Kosmider, Olivier, Gelsi-Boyer, Véronique, Cheok, Meyling, Grabar, Sophie, Della-Valle, Véronique, Picard, Françoise, Viguié, Franck, Quesnel, Bruno, Beyne-Rauzy, Odile, Solary, Eric, Vey, Norbert, Hunault-Berger, Mathilde, Fenaux, Pierre, Mansat-De Mas, Véronique, Delabesse, Eric, Guardiola, Philippe, Lacombe, Catherine, Vainchenker, William, Preudhomme, Claude, Dreyfus, François, Bernard, Olivier A, Birnbaum, Daniel, Fontenay, Michaëla
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	United States 08.10.2009
Témata:	Aged Aged, 80 and over Disease-Free Survival DNA-Binding Proteins - genetics DNA-Binding Proteins - metabolism Female Follow-Up Studies Genetic Markers Humans Male Middle Aged Mutation Myelodysplastic Syndromes - genetics Myelodysplastic Syndromes - mortality Predictive Value of Tests Proto-Oncogene Proteins - genetics Proto-Oncogene Proteins - metabolism Risk Factors Survival Rate
ISSN:	1528-0020, 1528-0020
On-line přístup:	Zjistit podrobnosti o přístupu
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